isocitrate dehydrogenase

isocitrate dehydrogenase
isocitrate de·hy·dro·ge·nase -.dē-(.)hī-'dräj-e-.nās, -(')dē-'hī-drə-jə-, -.nāz n either of two enzymes which catalyze the oxidation of isocitric acid to alpha-ketoglutaric acid (as in the Krebs cycle) and of which one uses NAD as an electron acceptor and the other NADP called also isocitric dehydrogenase

Medical dictionary. 2011.

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  • Isocitrate dehydrogenase — (EC number|1.1.1.42) and (EC number|1.1.1.41), also known as IDH, is an enzyme which participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha ketoglutarate (α… …   Wikipedia

  • isocitrate dehydrogenase — isocitrate dehydrogenase. См. изоцитратдегидрогеназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • (isocitrate dehydrogenase (NADP+)) kinase — In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase (EC number|2.7.11.5) is an enzyme that catalyzes the chemical reaction::ATP + [isocitrate dehydrogenase (NADP+)] ightleftharpoons ADP + [isocitrate dehydrogenase (NADP+)] phosphateThus,… …   Wikipedia

  • isocitrate dehydrogenase (NAD+) — iso·ci·trate de·hy·dro·gen·ase (NAD+) (i″so sĭґtrāt de hiґdrə jən ās) [EC 1.1.1.41] a mitochondrial enzyme that catalyzes the oxidative decarboxylation of isocitrate to form α ketoglutarate, using NAD+ as an… …   Medical dictionary

  • isocitrate dehydrogenase (NADP+) — iso·ci·trate de·hy·dro·gen·ase (NADP+) (i″so sĭґtrāt de hiґdrə jən ās) [EC 1.1.1.42] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of isocitrate to form α ketoglutarate,… …   Medical dictionary

  • Dehydrogenase — A dehydrogenase (also called DHO in the literature) is an enzyme that oxidises a substrate by a reduction reaction that transfers one or more hydrides (H−) to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.… …   Wikipedia

  • dehydrogenase — Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors), which are thus reduced; most of the oxidative enzymes… …   Medical dictionary

  • isocitrate — A salt or ester of isocitric acid. i. dehydrogenase one of two enzymes that catalyze the conversion of threo ds i., the product of the action of both aconitase and i. lyase, to α ketoglutarate (2 oxoglutarate) and CO2; one of the isozymes uses …   Medical dictionary

  • Malate dehydrogenase — Structure of the protein with attached sugars Identifiers EC number …   Wikipedia

  • Succinate dehydrogenase — (ubiquinone) Subunits: SdhA, SdhB, SdhC and SdhD Identifiers EC number …   Wikipedia

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