isocitrate dehydrogenase (NADP+)
- isocitrate dehydrogenase (NADP+)
- iso·ci·trate de·hy·dro·gen·ase (NADP+) (i″so-sĭґtrāt de-hiґdrə-jən-ās) [EC 1.1.1.42] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of isocitrate to form α-ketoglutarate, using NADP+ as an electron acceptor. The enzyme exists as two isozymes, one cytoplasmic and one mitochondrial, requires Mg2+ or Mn2+, and occurs in all tissues. The reaction serves to maintain the level of reducing equivalents within the cell.
Medical dictionary.
2011.
Look at other dictionaries:
(isocitrate dehydrogenase (NADP+)) kinase — In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase (EC number|2.7.11.5) is an enzyme that catalyzes the chemical reaction::ATP + [isocitrate dehydrogenase (NADP+)] ightleftharpoons ADP + [isocitrate dehydrogenase (NADP+)] phosphateThus,… … Wikipedia
Isocitrate dehydrogenase — (EC number|1.1.1.42) and (EC number|1.1.1.41), also known as IDH, is an enzyme which participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha ketoglutarate (α… … Wikipedia
isocitrate dehydrogenase — isocitrate de·hy·dro·ge·nase .dē (.)hī dräj e .nās, ( )dē hī drə jə , .nāz n either of two enzymes which catalyze the oxidation of isocitric acid to alpha ketoglutaric acid (as in the Krebs cycle) and of which one uses NAD as an electron acceptor … Medical dictionary
Dehydrogenase — A dehydrogenase (also called DHO in the literature) is an enzyme that oxidises a substrate by a reduction reaction that transfers one or more hydrides (H−) to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.… … Wikipedia
isocitrate — A salt or ester of isocitric acid. i. dehydrogenase one of two enzymes that catalyze the conversion of threo ds i., the product of the action of both aconitase and i. lyase, to α ketoglutarate (2 oxoglutarate) and CO2; one of the isozymes uses … Medical dictionary
Malate dehydrogenase — Structure of the protein with attached sugars Identifiers EC number … Wikipedia
Succinate dehydrogenase — (ubiquinone) Subunits: SdhA, SdhB, SdhC and SdhD Identifiers EC number … Wikipedia
NADH dehydrogenase — Structure of NADH dehydrogenase Identifiers EC number 1.6.5.3 … Wikipedia
Oxoglutarate dehydrogenase complex — The oxoglutarate dehydrogenase complex (OGDC) or α ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric acid cycle. Contents 1 Units 2 Properties 2.1 Metabolic pathways 2.2 … Wikipedia
Alcohol dehydrogenase — Crystallographic structure of the homodimer of human ADH5.[1] Identifiers … Wikipedia
