lecithin–cholesterol acyltransferase

lecithin–cholesterol acyltransferase
(LCAT) lec·i·thin–cho·les·ter·ol ac·yl·trans·fer·ase (LCAT) (lesґĭ-thin kə-lesґtər-ol a″səl-transґfər-ās) phosphatidylcholine–sterol O-acyltransferase.

Medical dictionary. 2011.

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  • lecithin–cholesterol acyltransferase deficiency — le·ci·thin–cho·les·ter·ol ac·yl·trans·fer·ase de·fi·cien·cy (lesґĭ thin kə lesґtər ol a″səl transґfər ās) an autosomal recessive disorder due to failure of LCAT to esterify plasma cholesterol as the result of …   Medical dictionary

  • phosphatidylcholine–sterol O-acyltransferase — phos·pha·ti·dyl·cho·line–ster·ol O ac·yl·trans·fer·ase (fos″fə ti″dəl koґlēn sterґol a″səl transґfər ās) [EC 2.3.1.43] an enzyme of the transferase class, secreted by the liver, that catalyzes the …   Medical dictionary

  • reverse cholesterol transport — the process by which high density lipoproteins (HDL) facilitate the movement of cholesterol from peripheral cells back to the liver for excretion in the bile. Cholesterol released into plasma during cell turnover is adsorbed to HDL where it is… …   Medical dictionary

  • Norum-Gjone disease — lecithin–cholesterol acyltransferase deficiency …   Medical dictionary

  • LCAT deficiency — lecithin–cholesterol acyltransferase deficiency …   Medical dictionary

  • fish eye disease — a less severe form of lecithin–cholesterol acyltransferase deficiency due to a partial defect in the enzyme activity as a result of mutation in the LCAT gene (locus: 16q22.1); corneal opacities give the eye the appearance of the eye of a boiled …   Medical dictionary

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