reverse cholesterol transport

reverse cholesterol transport
the process by which high-density lipoproteins (HDL) facilitate the movement of cholesterol from peripheral cells back to the liver for excretion in the bile. Cholesterol released into plasma during cell turnover is adsorbed to HDL where it is esterified by lecithin–cholesterol acyltransferase; most of the cholesteryl esters then are transferred to intermediate-density or very-low-density lipoproteins by a specific transfer protein and these lipoproteins are ultimately taken up by the liver.

Medical dictionary. 2011.

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