syndrome of inappropriate secretion of antidiuretic hormone
- syndrome of inappropriate secretion of antidiuretic hormone
-
a condition of inappropriately high plasma levels of ADH (
see vasopressin) with associated water retention, dilutional
hyponatraemia,
and the production of highly concentrated urine. Renal, adrenal, thyroid, and hepatic function are normal, as is the volume of circulating blood (euvolaemia). It is caused by a variety of pathological conditions, usually intrathoracic and intracerebral, and also by a number of drugs, including antidepressants, chemotherapy agents, and some of the older antidiabetic agents. The treatment involves fluid restriction, treatment (or removal) of the underlying cause (or drug),
and,
in severe cases, administration of
demeclocycline to reduce the effects of ADH on the kidney. Very rarely, hypertonic saline is given.
Medical dictionary.
2011.
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Syndrome of inappropriate antidiuretic hormone — Infobox Disease Name = Syndrome of inappropriate antidiuretic hormone | Caption = DiseasesDB = 12050 ICD10 = ICD10|E|22|2|e|20 ICD9 = ICD9|253.6 ICDO = OMIM = MedlinePlus = 003702 eMedicineSubj = emerg eMedicineTopic = 784 eMedicine mult =… … Wikipedia
Antidiuretic hormone (ADH) — A relatively small (peptide) molecule that is released by the pituitary gland at the base of the brain after being made nearby (in the hypothalamus). ADH has an antidiuretic action that prevents the production of dilute urine (and so is… … Medical dictionary
syndrome of inappropriate antidiuresis — (SIAD) a disorder of sodium and water balance characterized by hyponatremia with hypovolemia and elevated urine osmolality in the absence of kidney disease; it may be caused by inappropriate secretion of vasopressin (s. of inappropriate… … Medical dictionary
ADH (antidiuretic hormone) — A peptide molecule that is released by the pituitary gland at the base of the brain after being made nearby (in the hypothalamus). ADH has an antidiuretic action that prevents the production of dilute urine (and so is antidiuretic). A syndrome of … Medical dictionary
syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… … Medical dictionary
ADH secretion, inappropriate — The syndrome of inappropriate secretion of antidiuretic hormone (ADH) results in the inability to put out dilute urine, perturbs fluid (and electrolyte) balance, and causes nausea, vomiting, muscle cramps, confusion and convulsions. This syndrome … Medical dictionary
Hormone, antidiuretic (ADH) — A relatively small (peptide) molecule that is released by the pituitary gland at the base of the brain after being made nearby (in the hypothalamus). ADH has an antidiuretic action that prevents the production of dilute urine (and so is… … Medical dictionary
Syndrome, paraneoplastic — A group of signs and symptoms due to a substance produced by a tumor or in reaction to the tumor. Paraneoplastic syndromes can be due to hormones (or other biologically active products) made by the tumor, blockade of the effect of a normal… … Medical dictionary
SIADH — syndrome of inappropriate secretion of antidiuretic hormone … The new mediacal dictionary
SIADH — • syndrome of inappropriate secretion of antidiuretic hormone … Dictionary of medical acronyms & abbreviations
