Syndrome, paraneoplastic

Syndrome, paraneoplastic
A group of signs and symptoms due to a substance produced by a tumor or in reaction to the tumor. Paraneoplastic syndromes can be due to hormones (or other biologically active products) made by the tumor, blockade of the effect of a normal hormone, autoimmunity, immune-complex production, immune suppression and other causes. By definition, paraneoplastic syndrome are not produced by the primary tumor or its metastases (or by compression, infection, nutritional deficiency or treatment of the tumor). A well-known paraneoplastic syndrome is the syndrome of inappropriate antidiuretic hormone (ADH) secretion which perturbs fluid balance, results in the inability to put out dilute urine and causes nausea, vomiting, muscle cramps, confusion and convulsions. Inappropriate ADH secretion can occur, for example, with oat-cell lung cancer, pancreatic cancer, prostate cancer, and Hodgkin's disease as well as a number of other disorders. "Para-" is a prefix with many meanings including "resembling, beyond, and apart from." "Neoplastic" means tumoral, pertaining to a tumor. "Paraneoplastic" is thus, resembling a tumor, near tumoral, apart from a tumor.

Medical dictionary. 2011.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Paraneoplastic syndrome — Classification and external resources DiseasesDB 2064 eMedicine med/1747 …   Wikipedia

  • paraneoplastic cerebellar degeneration — paraneoplastic subacute cerebellar degeneration the most common paraneoplastic syndrome affecting the brain, occurring most commonly with ovarian and breast carcinomas and Hodgkin disease, characterized pathologically by severe loss of Purkinje… …   Medical dictionary

  • Paraneoplastic syndrome — A group of signs and symptoms caused by a substance produced by a tumor or in reaction to a tumor. Paraneoplastic syndromes can be due to a number of causes including hormones or other biologically active products made by the tumor, blockade of… …   Medical dictionary

  • paraneoplastic — Relating to or characteristic of paraneoplasia. * * * para·neo·plas·tic .par ə .nē ə plas tik adj caused by or resulting from the presence of cancer in the body but not the physical presence of cancerous tissue in the part or organ affected… …   Medical dictionary

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • paraneoplastic opsoclonus — opsoclonus occurring as part of the paraneoplastic type of opsoclonus myoclonus syndrome (see under syndrome) …   Medical dictionary

  • paraneoplastic polyneuropathy — a paraneoplastic syndrome, sometimes seen with carcinoma, multiple myeloma, or Hodgkin disease, consisting of polyneuropathy with sensory or sensorimotor symptoms. Cf. carcinomatous pericarditis. Called also paraneoplastic neuropathy …   Medical dictionary

  • paraneoplastic syndrome — signs or symptoms occurring in a patient with cancer that result from antibodies produced by the cancer and are not due directly to local effects of the cancer cells. Examples are myasthenia gravis secondary to a tumour of the thymus, a… …   The new mediacal dictionary

  • paraneoplastic — par·a·ne·o·plas·tic (păr ə nē ə plăsʹtĭk) adj. Of or relating to a syndrome or other systemic disturbance associated with but not directly related to a primary tumor or its metastases. * * * …   Universalium

  • paraneoplastic acrokeratosis — Bazex syndrome …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”