delayed hypersensitivity

delayed hypersensitivity
de·layed hypersensitivity di-.lād- n hypersensitivity (as in a tuberculin test) which is mediated by T cells and in which the typical symptoms of inflammation and induration appear in an individual previously exposed to an antigen after an interval of 12 to 48 hours following a subsequent exposure (as by injection of the antigen under the skin)

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(DH), delayed-type hypersensitivity (DTH) a type of hypersensitivity that (in contrast to immediate h.) takes 24 to 72 hours to develop and is mediated by T lymphocytes rather than by antibodies; the term is usually used to denote the subset of type IV hypersensitivity involving cytokine release and macrophage activation, as opposed to direct cytolysis, but can be used more broadly, even sometimes being used synonymously with type IV h. (q.v.).

Medical dictionary. 2011.

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  • delayed hypersensitivity cells — delayed hypersensitivity cells. = TDH lymphocytes (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • delayed hypersensitivity cells — delayed hypersensitivity cells. См. ТDH лимфоциты. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • delayed hypersensitivity reaction — a reaction of cell mediated immunity, named in contrast to immediate hypersensitivity reactions because its onset is 24 to 72 hours after the antigenic challenge; the term is usually used to denote the subset of type IV hypersensitivity reactions …   Medical dictionary

  • hypersensitivity — In immunology, a state of excessive and potentially damaging immune responsiveness as a result of previous exposure to antigen. If the hypersensitivity is of the immediate type (antibody mediated), then the response occurs in minutes; in delayed… …   Dictionary of molecular biology

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  • hypersensitivity — Abnormal sensitivity, a condition in which there is an exaggerated response by the body to the stimulus of a foreign agent. See allergy. contact h. 1. SYN: contact dermatitis. 2. SYN: delayed reaction. delayed h. 1 …   Medical dictionary

  • type IV hypersensitivity — hypersensitivity initiated by antigen specific T lymphocytes; unlike forms mediated by antibodies, it takes one or more days to develop and can be transferred by lymphocytes but not by serum. The term is often equated with delayed… …   Medical dictionary

  • delayed-type hypersensitivity — See hypersensitivity …   Dictionary of molecular biology

  • delayed allergy — see under hypersensitivity …   Medical dictionary

  • immediate hypersensitivity reaction — 1. type I hypersensitivity r. 2. occasionally, any hypersensitivity reaction mediated by antibodies and developing rapidly, generally in minutes to hours (i.e., type I, II, or III hypersensitivity r.), as distinguished from those mediated by T… …   Medical dictionary

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