type IV hypersensitivity

type IV hypersensitivity
hypersensitivity initiated by antigen-specific T lymphocytes; unlike forms mediated by antibodies, it takes one or more days to develop and can be transferred by lymphocytes but not by serum. The term is often equated with delayed hypersensitivity, although the latter is sometimes restricted to hypersensitivity involving cytokine-mediated reactions (as contrasted with direct cytolysis). See type IV hypersensitivity reaction, under hypersensitivity reaction, at reaction. Called also cell- or T cell–mediated h.

Medical dictionary. 2011.

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  • type I hypersensitivity — hypersensitivity that occurs rapidly (within several minutes) upon reexposure to an antigen, due to interaction of IgE and the antigen; see type I hypersensitivity reaction, under hypersensitivity reaction, at reaction …   Medical dictionary

  • type II hypersensitivity — hypersensitivity resulting from antibody antigen interactions on cell surfaces; see type II hypersensitivity reaction, under hypersensitivity reaction, at reaction. Called also antibody mediated h …   Medical dictionary

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  • Type II hypersensitivity — In type II hypersensitivity (or cytotoxic hypersensitivity)cite web |url=http://pathmicro.med.sc.edu/ghaffar/hyper00.htm |title=Hypersensitivity reactions |format= |work= |accessdate=] the antibodies produced by the immune response bind to… …   Wikipedia

  • type IV hypersensitivity — A delayed hypersensitivity response (it appears 24 to 48 hours after antigen exposure). It results from the binding of antigen to activated T lymphocytes, which then release cytokines and trigger inflammation and macrophage attacks that damage… …   Dictionary of microbiology

  • Type V hypersensitivity reaction — A Type V hypersensitivity reaction occurs when IgG class antibodies directed towards cell surface antigens have a stimulating effect on their target.Grave s disease is an example of this type of hypersensitivity reaction. This disease is also… …   Wikipedia

  • type I hypersensitivity — A form of immediate hypersensitivity arising from the binding of antigen to IgE attached to mast cells, which then release anaphylaxis mediators such as histamine. Examples: hay fever, asthma, and food allergies …   Dictionary of microbiology

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