An autoantibody-like immunoglobulin (IgM) formed in animals (or man) against their own complement following injection of complement-containing complexes or sensitized bacteria.

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im·mu·no·con·glu·ti·nin -kən-'glüt-ən-in n an autoantibody formed by an organism against its own complement

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im·mu·no·con·glu·ti·nin (im″u-no-kən-glooґtĭ-nin) an autoantibody, usually of the immunoglobulin M class, that is specific for activated C3 and C4 components of complement. It is found in low titer in most normal sera and in increased levels in certain infectious diseases, in autoimmune disease, and after immunization with many antigens. Not to be confused with conglutinin. Called also immune conglutinin.

Medical dictionary. 2011.

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Look at other dictionaries:

  • immunoconglutinin — Antibodies that react with complement components or their breakdown products. Usually directed against C3b or C4, and found in high titre in patients with rheumatoid arthritis …   Dictionary of molecular biology

  • I-K — immunoconglutinin …   Medical dictionary

  • immune conglutinin — immunoconglutinin …   Medical dictionary

  • I-K — • immunoconglutinin …   Dictionary of medical acronyms & abbreviations

  • conglutination — 1. SYN: adhesion (1). 2. Agglutination of antigen(erythrocyte) antibody complement complex by normal bovine serum (and certain other colloidal materials); the procedure provides a means of detecting the presence of nonagglutinating antibody. * *… …   Medical dictionary

  • conglutinin — Bovine serum protein that, when absorbed by erythrocyte antibody complement complexes, causes them to agglutinate; it is comparatively thermostable and apparently dissociates when diluted with physiologic saline solution. SYN: bovine colloid. * * …   Medical dictionary

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