granulocyte series

granulocyte series
granulocytic series the succession of morphologically distinguishable cells that are stages in granulocyte development; after the colony-forming unit–granulocyte-macrophage, the stages in order of maturity are the myeloblast, promyelocyte, myelocyte, and metamyelocyte, followed by the band or stab cell, which is the least mature form normally found in the peripheral blood, and the mature segmented (polymorphonuclear) granulocyte. Commitment to one of the granulocyte lines occurs in stem cells before the myeloblast stage, so that there are distinct basophilic, eosinophilic, and neutrophilic series, although all three include the same morphologic stages. Formerly called the myelocytic, myeloid, or leukocytic s.

Several stages of the granulocytic series. D, Neutrophilic metamyelocyte; P, promyelocyte; N, neutrophilic band cell.


Medical dictionary. 2011.

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