sarcosine dehydrogenase

sarcosine dehydrogenase
sar·co·sine de·hy·dro·gen·ase (sahrґko-sēn de-hiґdro-jən-ās) [EC 1.5.99.1] a mitochondrial enzyme of the oxidoreductase class that catalyzes the oxidative demethylation of sarcosine to form glycine; electrons are transferred via its flavin (FAD) cofactor to electron transfer flavoprotein. Folate is also a cofactor. The reaction occurs in the inner mitochondrial membrane in liver and kidney; deficiency of the enzyme, an autosomal recessive trait, results in sarcosinemia.

Medical dictionary. 2011.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Sarcosine dehydrogenase — In enzymology, a sarcosine dehydrogenase (EC number|1.5.99.1) is an enzyme that catalyzes the chemical reaction:sarcosine + acceptor + H2O ightleftharpoons glycine + formaldehyde + reduced acceptorThe 3 substrates of this enzyme are sarcosine,… …   Wikipedia

  • Sarcosine — IUPAC name 2 (Methylamino)acetic acid …   Wikipedia

  • sarcosine — N Methylglycine; an intermediate in the metabolism of choline; it can donate a methyl group to tetrahydrofolate, yielding N5,N10 methylenetetrahydrofolate; demethylation by s. dehydrogenase yields formaldehyde, glycine, and a reduced acceptor;… …   Medical dictionary

  • Dimethylglycine dehydrogenase — Identifiers EC number 1.5.99.2 CAS number 37256 30 7 …   Wikipedia

  • NADH dehydrogenase — Structure of NADH dehydrogenase Identifiers EC number 1.6.5.3 …   Wikipedia

  • Dihydrolipoamide dehydrogenase — PDB rendering based on 1zy8 …   Wikipedia

  • dimethylglycine dehydrogenase — di·meth·yl·gly·cine de·hy·dro·gen·ase (di meth″əl gliґsēn de hiґdro jən ās) [EC 1.5.99.2] a mitochondrial flavoprotein enzyme of the oxidoreductase class that catalyzes the oxidative demethylation of N,N dimethylglycine… …   Medical dictionary

  • SARDH — Sarcosine dehydrogenase, also known as SARDH, is a human gene.cite web | title = Entrez Gene: SARDH sarcosine dehydrogenase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=1757| accessdate = ] PBB Summary… …   Wikipedia

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Oxidoreductase — In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen or electron donor) to another (the oxidant, also called the hydrogen or electron acceptor). This… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”