sarcosine

sarcosine
N-Methylglycine; an intermediate in the metabolism of choline; it can donate a methyl group to tetrahydrofolate, yielding N5,N10-methylenetetrahydrofolate; demethylation by s. dehydrogenase yields formaldehyde, glycine, and a reduced acceptor; elevated in certain inherited disorders.
- s. dehydrogenase an enzyme that cleaves s. using some acceptor to produce glycine, formaldehyde, and a reduced acceptor molecule; a deficiency of this enzyme will result in sarcosinemia.

* * *

sar·co·sine 'sär-kə-.sēn, -sən n a sweetish crystalline amino acid C3H7NO2 formed by the decomposition of creatine or made synthetically

* * *

sar·co·sine (sahrґko-sēn) an amino acid occurring as an intermediate in the metabolism of choline in the kidney and liver; it is normally not detectable in human blood or urine.

Medical dictionary. 2011.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Sarcosine — IUPAC name 2 (Methylamino)acetic acid …   Wikipedia

  • Sarcosine — Général No CAS …   Wikipédia en Français

  • sarcosine — sarcosine. См. саркозин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • sarcosine — [saʀkozin] n. f. ÉTYM. 1876, in P. Larousse; de sarco , et ine. ❖ ♦ Chim., biol. Dérivé méthylé du glycocolle présent dans les muscles, résultant de la dégradation de certains acides aminés et de la créatine …   Encyclopédie Universelle

  • sarcosine — sarkozinas statusas T sritis chemija formulė CH₃NHCH₂COOH santrumpa( os) Sar atitikmenys: angl. sarcosine rus. саркозин ryšiai: sinonimas – metilaminoetano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • Sarcosine oxidase — is an enzyme (EC number|1.5.3.1) that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5,10 CH2 tetrahydrofolate in a reaction requiring H4 tetrahydrofolate and oxygen. Corynebacterial sarcosine oxidase is a… …   Wikipedia

  • Sarcosine dehydrogenase — In enzymology, a sarcosine dehydrogenase (EC number|1.5.99.1) is an enzyme that catalyzes the chemical reaction:sarcosine + acceptor + H2O ightleftharpoons glycine + formaldehyde + reduced acceptorThe 3 substrates of this enzyme are sarcosine,… …   Wikipedia

  • Sarcosine reductase — In enzymology, a sarcosine reductase (EC number|1.21.4.3) is an enzyme that catalyzes the chemical reaction:acetyl phosphate + methylamine + thioredoxin disulfide ightleftharpoons N methylglycine + phosphate + thioredoxinThe 3 substrates of this… …   Wikipedia

  • sarcosine dehydrogenase — sar·co·sine de·hy·dro·gen·ase (sahrґko sēn de hiґdro jən ās) [EC 1.5.99.1] a mitochondrial enzyme of the oxidoreductase class that catalyzes the oxidative demethylation of sarcosine to form glycine; electrons are transferred via… …   Medical dictionary

  • sarcosine — /sahr keuh seen , sin/, n. Chem. a crystalline compound, C3H7NO2, with a sweet taste, soluble in water, slightly soluble in alcohol: used in the manufacture of toothpaste, cosmetics, and pharmaceuticals. [ < G Sarkosin (1847), appar. irregular… …   Universalium

  • sarcosine — noun The amino acid N methyl glycine; it is present in most tissue, and has a number of industrial applications …   Wiktionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”