Medical dictionary. 2011.
Transcription-coupled repair — is a DNA repair mechanism which operates in tandem with transcription. The activity of TCR has been known for 20 years, but its mechanism of action is an area of current research. Failure of the transcription coupled repair is the cause of… … Wikipedia
Nucleotide excision repair — Diagram[1] Nucleotide excision repair is a DNA repair mechanism.[2] DNA constantly requires r … Wikipedia
DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… … Wikipedia
DNA mismatch repair — is a system for recognizing and repairing erroneous insertion, deletion and mis incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.[1][2] Mismatch repair is strand… … Wikipedia
Postreplication repair — is the repair of damage to the DNA that takes place after replication. Some example genes in humans include: BRCA2 and BRCA1 BLM NBS1 DNA damage prevents the normal enzymatic synthesis of DNA by the replication fork.[1][2][3][4] … Wikipedia
Excision repair — is a term applied to several DNA repair mechanisms.Excision repair mechanisms that remove the damaged nucleotide replacing it with an undamaged nucleotide complementary to the nucleotide in the undamaged DNA strand. These include: *Base excision… … Wikipedia
nucleotide excision repair — (NER) repair of bulky lesions introduced into DNA by damage, such as that induced by ultraviolet light; at least 30 proteins are involved and the process consists of recognition of the lesion, strand separation at the site, single strand incision … Medical dictionary
global genome repair — (GGR) the form of nucleotide excision repair (q.v.) occurring throughout the genome; a complex of proteins identifies DNA damage by detection of distortions in the DNA helix. A variety of mutations affecting this pathway have been associated with … Medical dictionary
AP-1 (transcription factor) — In molecular biology, the activator protein 1 (AP 1) is a transcription factor which is a heterodimeric protein composed of proteins belonging to the c Fos, c Jun, ATF and JDP families. AP 1 upregulates transcription of genes containing the TPA… … Wikipedia
ERCC8 (gene) — Excision repair cross complementing rodent repair deficiency, complementation group 8, also known as ERCC8, is a human gene.cite web | title = Entrez Gene: ERCC8 excision repair cross complementing rodent repair deficiency, complementation group… … Wikipedia
