global genome repair

global genome repair
(GGR) the form of nucleotide excision repair (q.v.) occurring throughout the genome; a complex of proteins identifies DNA damage by detection of distortions in the DNA helix. A variety of mutations affecting this pathway have been associated with xeroderma pigmentosum. Cf. transcription-coupled r.

Medical dictionary. 2011.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Nucleotide excision repair — Diagram[1] Nucleotide excision repair is a DNA repair mechanism.[2] DNA constantly requires r …   Wikipedia

  • nucleotide excision repair — (NER) repair of bulky lesions introduced into DNA by damage, such as that induced by ultraviolet light; at least 30 proteins are involved and the process consists of recognition of the lesion, strand separation at the site, single strand incision …   Medical dictionary

  • transcription-coupled repair — (TCR) the form of nucleotide excision repair (q.v.) acting on the transcribed strand of genes; blocking of RNA polymerase progression by DNA damage initiates the repair process. Mutations affecting this pathway have been associated with Cockayne… …   Medical dictionary

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

  • GGR — global genomic repair * * * global genome repair …   Medical dictionary

  • xeroderma pigmentosum — xeroderma pig·men·to·sum .pig mən tō səm, .men n a genetic condition inherited as a recessive autosomal trait that is caused by a defect in mechanisms that repair DNA mutations (as those caused by ultraviolet light) and is characterized by the… …   Medical dictionary

  • Basenexzisionsreparatur — Durch DNA Reparatur Mechanismen können Zellen schadhafte Veränderungen der DNA Struktur in einer Zelle beseitigen. Solche Schäden in der DNA können spontan im Verlauf der DNA Replikation oder durch die Einwirkung mutagener Substanzen, extremer… …   Deutsch Wikipedia

  • DNA-Reparatur — Übergeordnet DNA Metabolismus Untergeordnet Einzelstrangbruch Reparatur Doppelstrangbruch Reparatur Postreplikations Reparatur Virale …   Deutsch Wikipedia

  • DNA-Reparaturmechanismus — Durch DNA Reparatur Mechanismen können Zellen schadhafte Veränderungen der DNA Struktur in einer Zelle beseitigen. Solche Schäden in der DNA können spontan im Verlauf der DNA Replikation oder durch die Einwirkung mutagener Substanzen, extremer… …   Deutsch Wikipedia

  • DNA-Schaden — Durch DNA Reparatur Mechanismen können Zellen schadhafte Veränderungen der DNA Struktur in einer Zelle beseitigen. Solche Schäden in der DNA können spontan im Verlauf der DNA Replikation oder durch die Einwirkung mutagener Substanzen, extremer… …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”