classical complement pathway

classical complement pathway
the enzymatic cascade containing all the components of complement, C1 through C9, primarily activated by the binding of C1 to antigen-antibody complexes containing IgM, IgG1, IgG2, or IgG3. See illustration at complement. The term is sometimes used to denote specifically those steps occurring prior to initiation of formation of the membrane attack complex (C5–C9).

Medical dictionary. 2011.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Classical complement pathway — The classical and alternative complement pathways. The Classical pathway of activation of the complement system is a group of blood proteins that mediate the specific antibody response. The main activators of the Classical Pathway are antigen… …   Wikipedia

  • classical complement pathway — The antibody dependent pathway of complement activation; it leads to the lysis of pathogens and stimulates phagocytosis and other host defenses …   Dictionary of microbiology

  • Alternative complement pathway — The classical and alternative complement pathways. Alternative pathway …   Wikipedia

  • alternative complement pathway — a pathway of complement activation initiated by a variety of factors other than those initiating the classical complement pathway, including IgA immune complexes, bacterial endotoxins, microbial polysaccharides, and cell walls. It does not… …   Medical dictionary

  • alternative complement pathway — An antibody independent pathway of complement activation that includes the C3 C9 components of the classical pathway and several other serum protein factors (e.g., factor B and properdin) …   Dictionary of microbiology

  • Complement system — This article is about an aspect of the immune system. For other uses, see complement (disambiguation). The complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of… …   Wikipedia

  • complement — Ehrlich term for the thermolabile substance, normally present in serum, that is destructive to certain bacteria and other cells sensitized by a specific c. fixing antibody. C. is a group of at least 20 distinct serum proteins, the …   Medical dictionary

  • Complement component 3 — PDB rendering based on 1c3d …   Wikipedia

  • Mannan-binding lectin pathway — Natta projection of mannose in its α D mannopyranose form. Mannan is a polymer of mannose. The Mannan binding lectin pathway (also known simply as the Lectin Pathway) is similar in structure to the classical complement pathway,[1] …   Wikipedia

  • Complement component 5 — PDB rendering based on 3cu7. Available st …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”