alternative complement pathway
- alternative complement pathway
- a pathway of complement activation initiated by a variety of factors other than those initiating the classical complement pathway, including IgA immune complexes, bacterial endotoxins, microbial polysaccharides, and cell walls. It does not include factors C1, C2, and C4 of the classical complement pathway but does include factors B and D and properdin. See illustration at complement. The term is sometimes used to denote specifically those steps occurring prior to initiation of formation of the membrane attack complex (C5–C9).
Medical dictionary.
2011.
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