Waldenstrцm macroglobulinemia
- Waldenstrцm macroglobulinemia
- a plasma cell dyscrasia resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, that secrete an IgM M component. There is diffuse infiltration of bone marrow and often the spleen, liver, lymph nodes, or central nervous system (Bing-Neel syndrome). The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances; peak incidence is in the sixth and seventh decades.
Medical dictionary.
2011.
Look at other dictionaries:
Waldenstrцm macroglobulinemia purpura — Wal·den·strцm macroglobulinemia, purpura (vahlґden strəm) [Jan Gosta Waldenstrцm, Swedish physician, 1906–1996] see under macroglobulinemia and purpura … Medical dictionary
chlorambucil — A nitrogen mustard derivative that depresses lymphocytic proliferation and maturation. SYN: chloraminophene, chloroambucil. * * * chlo·ram·bu·cil klōr am byə .sil, klȯr n an anticancer drug C14H19Cl2NO2 that … Medical dictionary
macroglobulin — mac·ro·glob·u·lin .mak rō gläb yə lən n a highly polymerized globulin (as IgM) of high molecular weight * * * n. 1. (immunoglobulin M, IgM) a protein of the globulin series that is present in the blood and functions as an antibody, forming an… … Medical dictionary
plasma cell dyscrasias — a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have… … Medical dictionary
benign monoclonal gammopathy — the presence of a serum M component without signs or symptoms of multiple myeloma, Waldenstrцm macroglobulinemia, or other plasma cell neoplasms; it occurs in about 3 per cent of the population over age 70. A few patients eventually develop a… … Medical dictionary
lymphoplasmacytic lymphoma — lymphoplasmacytoid lymphoma a heterogeneous group of low grade B cell lymphomas characterized by a mixture of small lymphocytes and plasmacytoid lymphocytes; it is sometimes associated with Waldenstrцm macroglobulinemia and can involve a number… … Medical dictionary
plasmacytoid lymphocytic lymphoma — a rare type of small lymphocytic lymphoma in which the predominant cell type is the plasma cell; it may be the manifestation in lymphoid tissue of Waldenstrцm macroglobulinemia in the blood … Medical dictionary
pyroglobulinemia — py·ro·glob·u·lin·emia (pi″ro glob″u lin eґme ə) the presence of pyroglobulin in the blood, occurring most frequently in multiple myeloma, Waldenstrцm macroglobulinemia, and other lymphoproliferative disorders, although it… … Medical dictionary
Bing-Neel syndrome — the central nervous system manifestations of Waldenstrцm macroglobulinemia; symptoms may include encephalopathy, hemorrhage, stroke, convulsions, delirium, and coma … Medical dictionary
