plasma cell dyscrasias

plasma cell dyscrasias
a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocyte morphology or a combination of lymphocytic and plasma cellular. The group includes multiple myeloma, Waldenstrцm macroglobulinemia, the heavy chain diseases, and benign monoclonal gammopathy. Called also dysproteinemias, monoclonal gammopathies or immunoglobulinopathies, and paraproteinemias.

Medical dictionary. 2011.

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