immunodeficiency with elevated IgM

immunodeficiency with elevated IgM
immunodeficiency with hyper-IgM a rare syndrome characterized by elevated immunoglobulin M levels and decreased levels of G and A immunoglobulins, associated with recurrent pyogenic infections, and possibly caused by failure of IgM-producing cells to switch to production of IgC and IgA. Most cases appear to exhibit X-linked recessive inheritance.

Medical dictionary. 2011.

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