hydroperoxyeicosatetraenoic acid
- hydroperoxyeicosatetraenoic acid
- (HPETE) hy·dro·per·oxy·ei·co·sa·tet·ra·eno·ic ac·id (HPETE) (hi″dro-pər-ok″se-i-ko″sə-tet″rə-e-noґik) any of several arachidonic acid metabolites produced by the actions of lipoxygenases. 5-HPETE (5-hydroperoxy-6,8,11,14-eicosatetraenoic acid) is the precursor of the leukotrienes. 12-HPETE (12-hydroperoxy-5,8,10,14-eicosatetraenoic acid) is the precursor of 12-HETE, which is chemotactic for neutrophils and eosinophils. 15-HPETE is the precursor of 15-HETE and of lipoxins.
Medical dictionary.
2011.
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Arachidonic acid 5-hydroperoxide — Chembox new ImageFile=5 Hydroperoxyeicosatetraenoic acid.svg ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=74581 83 2 PubChem=5280778 SMILES= MeSHName=Arachidonic+acid+5 hydroperoxide Section2= Chembox Properties… … Wikipedia
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hydroxyeicosatetraenoic acid — (HETE) hy·droxy·ei·co·sa·tet·ra·eno·ic ac·id (HETE) (hi drok″se i ko″sə tet″rə e noґik) any of several arachidonic acid metabolites produced by lipoxygenases from hydroperoxyeicosatetraenoic acid. 5 HETE is a byproduct … Medical dictionary
Leukotriene — Leukotrienes are naturally produced eicosanoid lipid mediators, which may be responsible for the effects of an inflammatory response. Leukotrienes use both autocrine signalling and paracrine signalling to regulate the body s response.… … Wikipedia
Arachidonate 5-lipoxygenase — (5 lipoxygenase, 5 LO or Alox5) is a human enzyme, member of the lipoxygenase family. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.ubstrates and productsEFA substrates and… … Wikipedia
Eicosanoid biosynthesis — Eicosanoids are signaling molecules, synthesized by most living creatures. (The IUPAC and the IUBMB use the equivalent term Icosanoid.cite web author=Cyberlipid Center| title=Prostanoids url= http://www.cyberlipid.org/prost1/pros0001.htm#9 |… … Wikipedia
ALOX15B — Arachidonate 15 lipoxygenase, type B, also known as ALOX15B, is a human gene.cite web | title = Entrez Gene: ALOX15B arachidonate 15 lipoxygenase, type B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=247| … Wikipedia
lipoxygenase pathway — a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acids from arachidonic acid. It is initiated by oxidation of arachidonic acid by arachidonate lipoxygenases, and the reactions occur in the cytosol of leukocytes, mast cells … Medical dictionary
arachidonate 12-lipoxygenase — arach·i·don·ate 12 lip·oxy·gen·ase (ə rakґĭ don″āt lĭ pokґsə jən ās) [EC 1.13.11.31] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 12 position to form 12… … Medical dictionary
arachidonate 15-lipoxygenase — arach·i·don·ate 15 lip·oxy·ge·nase (ə rakґĭ donґāt lĭ pokґsə jən ās) [EC 1.13.11.33] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 15 position to form 15… … Medical dictionary
