hydroxyeicosatetraenoic acid
- hydroxyeicosatetraenoic acid
- (HETE) hy·droxy·ei·co·sa·tet·ra·eno·ic ac·id (HETE) (hi-drok″se-i-ko″sə-tet″rə-e-noґik) any of several arachidonic acid metabolites produced by lipoxygenases from hydroperoxyeicosatetraenoic acid. 5-HETE is a byproduct of leukotriene metabolism. 12-HETE and 5,12-HETE are chemotactic for neutrophils and eosinophils and 12-HETE and 15-HETE may inhibit leukotriene production.
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2011.
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hydroxyeicosatetraenoic acid — noun A hydroxy derivative of a polyunsaturated fatty acid; it is an intermediate in the biosynthesis of leukotrienes … Wiktionary
5-hydroxyeicosatetraenoic acid — (5 HETE) is an endogenous eicosanoid.Functions5 HETE is a step in the pathway of leukotriene synthesis. In addition, it is a modulator of tubuloglomerular feedback … Wikipedia
arachidonic acid — (= 5,8,11,14 eicosatetraenoic acid) An essential dietary component for mammals. The free acid is the precursor for biosynthesis of the signalling molecules prostaglandins, thromboxanes, hydroxyeicosatetraenoic acid derivatives including… … Dictionary of molecular biology
HETE — • hydroxyeicosatetraenoic [acid] … Dictionary of medical acronyms & abbreviations
HETE — hydroxyeicosatetraenoic [acid] * * * hydroxyeicosatetraenoic acid … Medical dictionary
HETE — Hydroxyeicosatetraenoic acid (Ácido hidroxieicosatetraenoico) … Diccionario de siglas médicas y otras abreviaturas
lipoxygenase pathway — a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acids from arachidonic acid. It is initiated by oxidation of arachidonic acid by arachidonate lipoxygenases, and the reactions occur in the cytosol of leukocytes, mast cells … Medical dictionary
CYP4A11 — Cytochrome P450, family 4, subfamily A, polypeptide 11, also known as CYP4A11, is a human gene.cite web | title = Entrez Gene: CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… … Wikipedia
Leukotriene — Leukotrienes are naturally produced eicosanoid lipid mediators, which may be responsible for the effects of an inflammatory response. Leukotrienes use both autocrine signalling and paracrine signalling to regulate the body s response.… … Wikipedia
Arachidonate 5-lipoxygenase — (5 lipoxygenase, 5 LO or Alox5) is a human enzyme, member of the lipoxygenase family. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.ubstrates and productsEFA substrates and… … Wikipedia