von Willebrand disease

von Willebrand disease
a congenital bleeding disorder, usually of autosomal dominant inheritance, characterized by deficiency of von Willebrand factor, with prolonged bleeding time and often impairment of adhesion of platelets on glass beads, associated with epistaxis and increased bleeding after trauma or surgery, menorrhagia, and postpartum bleeding. Several different types have been distinguished, ranging from mild to severe. Called also angiohemophilia, pseudohemophilia, vascular hemophilia, Minot-von Willebrand syndrome, and Willebrand syndrome.

Medical dictionary. 2011.

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  • von Willebrand disease — von Willebrand disease. См. болезнь фон Виллебранда. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Von Willebrand disease — Infobox Disease Name = Von Willebrand disease Caption = DiseasesDB = 14007 ICD10 = ICD10|D|68|0|d|65 ICD9 = ICD9|286.4 ICDO = OMIM = 193400 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 2419 MeshID = D014842Von Willebrand disease (vWD) is… …   Wikipedia

  • von Willebrand disease — ▪ pathology       inherited blood disorder (blood disease) characterized by a prolonged bleeding time and a deficiency of factor VIII, an important blood clotting agent. This disorder is due to deficiencies in von Willebrand factor (vWF), a… …   Universalium

  • von Willebrand disease factor — von Wil·le·brand disease, factor (fōn vilґə brahnt) [Erik Adolf von Willebrand, Finnish physician, 1870–1949] see under disease and factor …   Medical dictionary

  • von Willebrand disease — noun An hereditary disease, characterized by a tendency to hemorrhage, and caused by a defect in blood platelet activity …   Wiktionary

  • Von Willebrand factor — (vWF) is a blood glycoprotein involved in hemostasis. It is deficient or defective in von Willebrand disease and is involved in a large number of other diseases, including thrombotic thrombocytopenic purpura, Heyde s syndrome, and possibly… …   Wikipedia

  • von Willebrand factor — von Wil·le·brand factor vän vil ə .bränt n a protein secreted esp. by endothelial cells that circulates in blood plasma as a large variable aggregation consisting usu. of repeating dimers, that mediates platelet adhesion to collagen in… …   Medical dictionary

  • von Willebrand — E.A., Finnish physician, 1870–1949. See von Willebrand disease …   Medical dictionary

  • von Willebrand's disease — von Wil·le·brand s disease .bränts n a genetic disorder that is caused by deficient or defective von Willebrand factor, is characterized by mucosal and petechial bleeding due to abnormal blood vessels, and is inherited chiefly as an autosomal… …   Medical dictionary

  • Minot-von Willebrand syndrome — von Willebrand disease …   Medical dictionary

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