von Willebrand's disease

von Willebrand's disease
von Wil·le·brand's disease -.bränts- n a genetic disorder that is caused by deficient or defective von Willebrand factor, is characterized by mucosal and petechial bleeding due to abnormal blood vessels, and is inherited chiefly as an autosomal dominant trait

Medical dictionary. 2011.

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  • von Willebrand's disease — an inherited disorder of the blood that is characterized by episodes of spontaneous bleeding similar to haemophilia. It is due to a variety of abnormalities of the von Willebrand factor, a glycoprotein necessary for normal platelet function. This …   Medical dictionary

  • von Willebrand's disease — an inherited disorder of the blood that is characterized by episodes of spontaneous bleeding similar to haemophilia. It is due to a variety of abnormalities of the von Willebrand factor, a glycoprotein necessary for normal platelet function. This …   The new mediacal dictionary

  • von Willebrand's disease — /fawn vil euh brahnts /, Pathol. an inherited autosomal recessive disease in which abnormally slow coagulation of blood may lead to spontaneous bleeding, excessive bleeding following an injury, and heavy menstrual flow. [1940 45; after Erik Adolf …   Universalium

  • von Willebrand's disease — noun a form of hemophilia discovered by Erik von Willebrand; a genetic disorder that is inherited as an autosomal recessive trait; characterized by a deficiency of the coagulation factor and by mucosal bleeding • Syn: ↑angiohemophilia, ↑vascular… …   Useful english dictionary

  • von Willebrand's disease — noun An hereditary disease, characterized by a tendency to hemorrhage, and caused by a defect in blood platelet activity …   Wiktionary

  • von Willebrand's disease — Autosomal dominant platelet disorder in which adhesion to collagen, but not aggregation, is reduced. Both bleeding time and coagulation are increased. Factor VIII levels are secondarily reduced …   Dictionary of molecular biology

  • Von Willebrand’s disease —  Genetic disorder that affects blood clotting …   Bryson’s dictionary for writers and editors

  • von Willebrand factor — von Wil·le·brand factor vän vil ə .bränt n a protein secreted esp. by endothelial cells that circulates in blood plasma as a large variable aggregation consisting usu. of repeating dimers, that mediates platelet adhesion to collagen in… …   Medical dictionary

  • von Willebrand factor — Plasma factor involved in platelet adhesion through an interaction with Factor VIII. See von Willebrand s disease …   Dictionary of molecular biology

  • Von Willebrand factor — (vWF) is a blood glycoprotein involved in hemostasis. It is deficient or defective in von Willebrand disease and is involved in a large number of other diseases, including thrombotic thrombocytopenic purpura, Heyde s syndrome, and possibly… …   Wikipedia

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