C4b2a

C4b2a
the classical pathway C3 convertase, which cleaves C3 to C3a and C3b, a complex of C4b and C2a formed on cell membrane surfaces in the presence of Mg2+. See also notes at C2a and complement.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • complement — Ehrlich term for the thermolabile substance, normally present in serum, that is destructive to certain bacteria and other cells sensitized by a specific c. fixing antibody. C. is a group of at least 20 distinct serum proteins, the …   Medical dictionary

  • C3-convertase — The classical and alternative complement pathways. There are two forms of C3 convertase (EC 3.4.21.43). The first is an enzyme composed of the C4b C2a complex, which forms during the classical or lectin pathways of the complement system …   Wikipedia

  • Komplementfaktoren — Schema der Komplementkaskade Das Komplementsystem ist ein System von Plasmaproteinen, das im Zuge der Immunantwort auf zahlreichen Oberflächen von Mikroorganismen aktiviert werden kann. Ursprünglich wurde es als ergänzender (komplementierender)… …   Deutsch Wikipedia

  • Sistema del complemento — Una proteína del complemento atacando una membrana celular. El sistema del complemento es uno de los componentes fundamentales de la respuesta inmunitaria defensiva ante un agente hostil (por ejemplo, microorganismos). Consta de un conjunto de… …   Wikipedia Español

  • C5-Konvertase — Enzymklassifikation EC, Kategorie …   Deutsch Wikipedia

  • Complement system — This article is about an aspect of the immune system. For other uses, see complement (disambiguation). The complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of… …   Wikipedia

  • Complement component 3 — PDB rendering based on 1c3d …   Wikipedia

  • Mannan-binding lectin pathway — Natta projection of mannose in its α D mannopyranose form. Mannan is a polymer of mannose. The Mannan binding lectin pathway (also known simply as the Lectin Pathway) is similar in structure to the classical complement pathway,[1] …   Wikipedia

  • MASP1 (protein) — protein Name = mannan binding lectin serine peptidase 1 (C4/C2 activating component of Ra reactive factor) caption = width = HGNCid = 6901 Symbol = MASP1 AltSymbols = CRARF, PRSS5 EntrezGene = 5648 OMIM = 600521 RefSeq = NM 001879 UniProt =… …   Wikipedia

  • Système du complément — Le système du complément est un groupe de 35 protéines connues du sérum, faisant partie de l immunité innée. 12 de ces protéines sont directement impliquées dans les mécanismes d élimination des pathogènes, les autres régulent finement l activité …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”