cerebroside-sulfatase

cerebroside-sulfatase
cer·e·bro·side-sul·fa·tase (sə-reґbro-sīd″ sulґfə-tās) [EC 3.1.6.8] an enzyme of the hydrolase class that catalyzes the cleavage of sulfate residues from sulfatides to form cerebrosides. Deficiency of the enzyme, an autosomal recessive trait, is one of the causes of metachromatic leukodystrophy. Called also arylsulfatase A.

Medical dictionary. 2011.

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  • Sulfatase — Pfam box Symbol = Sulfatase Name = width =200 caption =Steryl sulfatase Pfam= PF00884 InterPro= IPR000917 SMART= PROSITE = PDOC00117 SCOP = 1auk TCDB = OPM family= 24 OPM protein= 1p49 PDB=PDB3|1fsu :43 486 PDB3|1hdhB:3 501 PDB3|1p49A:25… …   Wikipedia

  • cerebroside — A class of glycosphingolipid; specifically, a monoglycosylceramide (ceramide monosaccharide), the sugar being attached to the CHOH moiety of the sphingoid. Cerebrosides are found in the myelin sheath of nerve tissue; e.g., kerasin, nervon,… …   Medical dictionary

  • sulfatase — 1. Trivial name for enzymes in EC group 3.1.6, the sulfuric ester hydrolases, which catalyze the hydrolysis of sulfuric esters (sulfates) to the corresponding alcohols plus inorganic sulfate; includes aryl , sterol, glycol , chondroitin, ch …   Medical dictionary

  • arylsulfatase A — cerebroside sulfatase …   Medical dictionary

  • Arylsulfatase A — PDB rendering based on 1auk …   Wikipedia

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • metachromatic leukodystrophy — n a hereditary neurological disorder of lipid metabolism characterized by the accumulation of cerebroside sulfates, loss of myelin in the central nervous system, and progressive deterioration of mental and motor activity * * * an autosomal… …   Medical dictionary

  • Arylsulfatase — is a type of sulfatase enzyme.[1] Types include: Arylsulfatase A (also known as cerebroside sulfatase ) Arylsulfatase B (also known as N Acetylgalactosamine 4 Sulfatase ) Steroid sulfatase (formerly known as Arylsulfatase C ) ARSC2 ARSD ARSE ARSF …   Wikipedia

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