Medical dictionary. 2011.
tissue-type plasminogen activator — tPA; = TPA a natural protein, found in the body and now able to be manufactured by genetic engineering (see alteplase), that can break up a thrombus (see thrombolysis). It requires the presence of fibrin as a cofactor and is able to activate… … The new mediacal dictionary
Tissue plasminogen activator — (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. Specifically, it is a serine protease (EC number|3.4.21.68) found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the… … Wikipedia
Plasminogen activator inhibitor-1 — Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 PAI 1 in complex with the SMB domain of Vitronectin PDB 1OC0 … Wikipedia
Plasminogen activator inhibitor-2 — Serpin peptidase inhibitor, clade B (ovalbumin), member 2 PDB rendering based on 1by7 … Wikipedia
tissue plasminogen activator — An enzyme made in the body that helps dissolve blood clots. A form of this enzyme is made in the laboratory to treat heart attacks, strokes, and clots in the lungs. It is also being studied in the treatment of cancer. Tissue plasminogen activator … English dictionary of cancer terms
recombinant tissue plasminogen activator — A form of tissue plasminogen activator that is made in the laboratory. It helps dissolve blood clots and is used to treat heart attacks, strokes, and clots in the lungs. It is also being studied in the treatment of cancer. It is a type of… … English dictionary of cancer terms
plasminogen activators — enzymes that convert the inactive substance plasminogen to the active enzyme plasmin, which digests blood clots (see fibrinolysis). There are two types of plasminogen activators, tissue type plasminogen activator (t PA) and urokinase like… … Medical dictionary
plasminogen activators — enzymes that convert the inactive substance plasminogen to the active enzyme plasmin, which digests blood clots (see fibrinolysis). There are two types of plasminogen activators, tissue type plasminogen activator (tPA) and urokinase like… … The new mediacal dictionary
activator — 1. A substance that renders another substance, or catalyst, active, or that accelerates a process or reaction. 2. The fragment, produced by chemical cleavage of a proactivator, that induces the enzymic activity of another … Medical dictionary
Adipose tissue — For the Doctor Who creatures, see List of Doctor Who monsters and aliens#Adipose. Adipose tissue is one of the main types of connective tissue. In histology, adipose tissue or body fat or fat depot or just fat is loose connective tissue composed… … Wikipedia
