One of the two major purines (the other being guanine) found in both RNA and DNA, and also in various free nucleotides of importance to the body, such as AMP (adenylic acid), ATP, NAD+ and NADP+, and FAD; in all these smaller compounds, a. is condensed with ribose at nitrogen-9, forming adenosine. For structure, see adenylic acid. SYN: 6-aminopurine.
- a. arabinoside misnomer for arabinosyladenine.
- a. deaminase an enzyme that catalyzes the hydrolysis of a. to ammonia and hypoxanthine. A part of purine degradation.
- a. phosphoribosyltransferase an enzyme that catalyzes the reaction of a. with 5-phospho-α-d-ribose 1-diphosphate (PRPP) to form AMP and pyrophosphate. An important step in purine salvage. A deficiency of this enzyme can lead to 2,8-dihydroxyadenine lithiasis.
- a. sulfate a. conjugated with sulfuric acid; used to stimulate leukocyte production in agranulocytosis.

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ad·e·nine 'ad-ən-.ēn n a purine base C5H5N5 that codes hereditary information in the genetic code in DNA and RNA compare CYTOSINE, GUANINE, THYMINE, URACIL

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one of the nitrogen-containing bases (see purine) that occurs in the nucleic acids DNA and RNA. See also ATP.

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ad·e·nine (adґə-nēn) 1. a major purine base (see illustration at base). In animal and plant cells it usually occurs condensed with ribose or deoxyribose to form the nucleosides adenosine and deoxyadenosine. As such, it is a component of nucleic acids, of certain nucleotides, and of many coenzymes. Symbol A. 2. [USP] a preparation of adenine used to improve the preservation of whole blood.

Medical dictionary. 2011.

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  • adénine — [ adenin ] n. f. • 1885 Adenin, en all.; du gr. adên « glande » et ine ♦ Biochim. Base azotée purique, l une des quatre bases essentielles des acides nucléiques. ● adénine nom féminin Base purique constitutive des acides nucléiques (A.D.N., A.R.N …   Encyclopédie Universelle

  • adenine — adenine. См. аденин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • adenine — (n.) crystaline base, 1885, coined by German physiologist/chemist Albrecht Kossel (1853 1927) from Gk. aden gland + chemical suffix INE (Cf. ine) (2). So called because it was derived from the pancreas of an ox …   Etymology dictionary

  • adenine — [ad′ə nēn΄, ad′ənin΄] n. [ ADEN(O) + INE3] a white, crystalline purine base, C5H5N5, contained in the DNA, RNA, and ADP of all tissue: it links with thymine in the DNA structure …   English World dictionary

  • Adenine — chembox ImageFile1 = Adenine chemical structure.png ImageSize1 = 150px ImageFileL2 = Adenine 3D balls.png ImageSizeL2 = 100px ImageFileR2 = Adenine 3D vdW.png ImageSizeR2 = 100px IUPACName = 9H purin 6 amine OtherNames = 6 aminopurine Section1 =… …   Wikipedia

  • Adenine (A) — One member of the A T (adenine thymine) base pair in DNA. The other base pair in DNA is G C (guanine cytosine). Each base pair forms a rung of the DNA ladder. A DNA nucleotide is made of a molecule of sugar, a molecule of phosphoric acid, and a… …   Medical dictionary

  • adenine — /ad n in, een , uyn /, n. Biochem. a purine base, C5H5N5, one of the fundamental components of nucleic acids, as DNA, in which it forms a base pair with thymine, and RNA, in which it pairs with uracil. Symbol: A [1880 85; < G Adenin; see ADEN ,… …   Universalium

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