HLA system

HLA system
human leucocyte antigen system: a series of four gene families (termed A, B, C, and D) that code for polymorphic proteins expressed on the surface of most nucleated cells. Individuals inherit from each parent one gene (or set of genes) for each subdivision of the HLA system. If two individuals have identical HLA types, they are said to be histocompatible. Successful tissue transplantation requires a minimum number of HLA differences between donor and recipient tissues.

Medical dictionary. 2011.

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  • HLA-System —   [HLA, Abkürzung für englisch human lymphocyte antigen], Histokompatibilitäts|antigen System, System von Oberflächenantigenen des Menschen, die durch mehrere eng gekoppelte Gene auf Chromosom 6 vererbt werden. Sie werden zusammen als MHC… …   Universal-Lexikon

  • HLA-System — [HLA ist Abk. für engl. human leucocyte antigen = menschliches Leukozytenantigen]: in die Membranen jeder Körperzelle eingebaute Antigene, die für die Gewebsverträglichkeit bei Transplantationen entscheidend sind …   Das Wörterbuch medizinischer Fachausdrücke

  • HLA-System — Lage der humanen Leukozyten Antigene auf dem Chromosom 6 mit seinen Genorten HLA A, B, C, DR, DQ und DP. Das humane Leukozytenantigen System (HLA System, HL Antigene, engl. Human Leukocyte Antigene ) ist der Name des humanen… …   Deutsch Wikipedia

  • HLA system — human leucocyte antigen system: a series of four gene families (termed A, B, C, and D) that code for polymorphic proteins expressed on the surface of most nucleated cells. Individuals inherit from each parent one gene (or set of genes) for each… …   The new mediacal dictionary

  • HLA-B — (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA B is part of a family of genes called the human leukocyte antigen (HLA) complex.… …   Wikipedia

  • HLA-DQ8 — (MHC Class II, DQ cell surface antigen) Rendering of HLA DQ8 with immundoinant insulin peptide in the binding pocket. Cis haplotype Haplotype …   Wikipedia

  • HLA-DR5 — (DR5) is a broad antigen serotype that is further split into HLA DR11 and HLA DR12 antigen serotypes.=Serology=With the exception of a few DRB1* alleles the reactivity of DR5 is relatively poor.=Disease associations=DR5 is associated with… …   Wikipedia

  • HLA-B44 — (B44) is an HLA B serotype. The serotype identifies the B*44 gene allele protein products of HLA B.cite journal | author = Marsh SG, Albert ED, Bodmer WF, et al | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue… …   Wikipedia

  • HLA-B15 — (B15) is an HLA B serotype. The serotype identifies the B*15 gene allele protein products of HLA B.cite journal | author = Marsh SG, Albert ED, Bodmer WF, et al | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue… …   Wikipedia

  • HLA-B14 — (B14) is a HLA B serotype. The serotype identifies the B*45 gene allele protein products of HLA B.cite journal | author = Marsh SG, Albert ED, Bodmer WF, et al | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens …   Wikipedia

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