pyruvate kinase

pyruvate kinase
pyruvate kinase n an enzyme that functions in glycolysis by catalyzing esp. the transfer of phosphate from phosphoenolpyruvate to ADP forming pyruvate and ATP

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py·ru·vate ki·nase (PK) (piґroo-vāt kiґnās) [EC 2.7.1.40] an enzyme of the transferase class that catalyzes the transfer of high energy phosphate from phosphoenolpyruvate to ADP to yield ATP and pyruvate. It is one of two reactions generating ATP in the Embden-Meyerhof pathway (see illustration under pathway) and a key regulatory site in this pathway. The enzyme has three distinct isozymes. Deficiency of pyruvate kinase activity in erythrocytes, an autosomal recessive trait, results in hemolytic anemia.

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  • Pyruvate kinase — is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP. ReactionThe reaction with pyruvate kinase: pyruvate kinase PEP > …   Wikipedia

  • Pyruvate kinase —   N° EC   …   Wikipédia en Français

  • pyruvate kinase — pyruvate kinase. См. пируваткиназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Pyruvate kinase deficiency — Infobox Disease Name = PAGENAME Caption = Phosphoenolpyruvate DiseasesDB = 11090 ICD10 = ICD10|D|55|2|d|55 ICD9 = ICD9|282.3 ICDO = OMIM = 266200 MedlinePlus = 001197 eMedicineSubj = med eMedicineTopic = 1980 MeshID = Pyruvate kinase deficiency,… …   Wikipedia

  • (pyruvate kinase)-phosphatase — In enzymology, a [pyruvate kinase] phosphatase (EC number|3.1.3.49) is an enzyme that catalyzes the chemical reaction: [pyruvate kinase] phosphate + H2O ightleftharpoons [pyruvate kinase] + phosphateThus, the two substrates of this enzyme are… …   Wikipedia

  • pyruvate kinase (PK) deficiency — py·ru·vate ki·nase (PK) de·fi·cien·cy (piґroo vāt kiґnās) an autosomal recessive disorder caused by mutation in the PKLR gene (locus: 1q21), which encodes the liver and erythrocyte isozymes of pyruvate kinase. It is the most common… …   Medical dictionary

  • Deficit en pyruvate kinase — Déficit en pyruvate kinase Le déficit en pyruvate kinase est une maladie (orpheline) à transmission autosomale récessive, c est à dire que les patients sont le plus souvent, en l absence de consanguinité, des hétérozygotes composites (les parents …   Wikipédia en Français

  • Déficit En Pyruvate Kinase — Le déficit en pyruvate kinase est une maladie (orpheline) à transmission autosomale récessive, c est à dire que les patients sont le plus souvent, en l absence de consanguinité, des hétérozygotes composites (les parents sont hétérozygotes et… …   Wikipédia en Français

  • Déficit en pyruvate kinase — Le déficit en pyruvate kinase est une maladie (orpheline) à transmission autosomale récessive, c est à dire que les patients sont le plus souvent, en l absence de consanguinité, des hétérozygotes composites (les parents sont hétérozygotes et… …   Wikipédia en Français

  • Pyruvate dehydrogenase complex — (PDC) is a complex of three enzymes that transform pyruvate into acetyl CoA by a process called pyruvate decarboxylation. Acetyl CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the… …   Wikipedia

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