pyruvate dehydrogenase

pyruvate dehydrogenase
pyruvate dehydrogenase n an enzyme that catalyzes the first step in the formation of acetyl coenzyme A from pyruvate by dehydrogenation in preparation for participation in the Krebs cycle

Medical dictionary. 2011.

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  • Pyruvate dehydrogenase — Crystallographic structure of pyruvate dehydrogenase (PDH). PH is a six domain dimer with α (blue), α’ (yellow), β (red), and β’ (teal) regions denoted by the different colors. Thiamine pyrophosphate (TPP) is shown in grey ball and stick form,… …   Wikipedia

  • pyruvate dehydrogenase — A complex multienzyme system that catalyses the conversion of (pyruvate + CoA + NAD+) to (acetyl CoA + CO2 + NAD) …   Dictionary of molecular biology

  • Pyruvate dehydrogenase complex — (PDC) is a complex of three enzymes that transform pyruvate into acetyl CoA by a process called pyruvate decarboxylation. Acetyl CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the… …   Wikipedia

  • Pyruvate dehydrogenase (lipoamide) alpha 1 — PDB rendering based on 1ni4 …   Wikipedia

  • Pyruvate dehydrogenase kinase — (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC number|2.7.11.2) is a kinase enzyme which acts to inactivate the enzyme pyruvate dehydrogenase by phosphorylating it using ATP. PDK thus participates in the regulation of the… …   Wikipedia

  • Pyruvate dehydrogenase deficiency — Classification and external resources ICD 10 E74.4 ICD 9 271.8 …   Wikipedia

  • Pyruvate dehydrogenase (NADP+) — EC number|1.2.1.51 is an enzyme that should not be confused with Pyruvate dehydrogenase (acetyltransferase) EC number|1.2.4.1.It catalyzes the following reaction::Pyruvate + Coenzyme A + NADP+ ⇒ acetyl CoA + NADPH + H+ + CO2 …   Wikipedia

  • (pyruvate dehydrogenase (acetyl-transferring))-phosphatase — In enzymology, a [pyruvate dehydrogenase (acetyl transferring)] phosphatase (EC number|3.1.3.43) is an enzyme that catalyzes the chemical reaction: [pyruvate dehydrogenase (acetyl transferring)] phosphate + H2O ightleftharpoons [pyruvate… …   Wikipedia

  • Pyruvate dehydrogenase (acetyl-transferring) — In enzymology, a pyruvate dehydrogenase (acetyl transferring) (EC number|1.2.4.1) is an enzyme that catalyzes the chemical reaction:pyruvate + [dihydrolipoyllysine residue acetyltransferase] lipoyllysine ightleftharpoons [dihydrolipoyllysine… …   Wikipedia

  • Pyruvate dehydrogenase (cytochrome) — In enzymology, a pyruvate dehydrogenase (cytochrome) (EC number|1.2.2.2) is an enzyme that catalyzes the chemical reaction:pyruvate + ferricytochrome b1 + H2O ightleftharpoons acetate + CO2 + ferrocytochrome b1The 3 substrates of this enzyme are… …   Wikipedia

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