olivopontocerebellar atrophy

olivopontocerebellar atrophy
ol·i·vo·pon·to·cer·e·bel·lar atrophy -.pän-tō-.ser-ə-'bel-ər- n an inherited disease esp. of mid to late life that is characterized by ataxia, hypotonia, dysarthria, and degeneration of the cerebellar cortex, middle cerebellar peduncles, and inferior olives called also olivopontocerebellar degeneration

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a form of multiple system atrophy in which neurodegeneration occurs in the cerebellar cortex, middle peduncles, ventral pontine surface, and olivary nuclei. It occurs in young to middle-aged persons and is characterized by ataxia, dysarthria, and parkinsonism. Both autosomal dominant and autosomal recessive types have been distinguished. Called also olivopontocerebellar degeneration and Dejerine-Thomas syndrome.

Medical dictionary. 2011.

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