Lewy body

Lewy body
Lewy body 'lü-ē-, 'lā-vē- n an eosinophilic inclusion body found in the cytoplasm of neurons of the cortex and brain stem in Parkinson's disease and some forms of dementia
Lew·ey 'lü-ē Frederic Henry (orig. Friedrich Heinrich Lewy ) (1885-1950)
American neurologist. Born in Berlin, Germany, Lewey oversaw German army field hospitals in France, Russia, and Turkey during World War I. He served as professor of clinical neurology at the University of Berlin's medical school from 1923 to 1933, researching occupational diseases of the nervous system and becoming director of the neurological institute in 1930. After emigrating to the U.S. in 1934, he became professor of neurophysiology at the University of Pennsylvania's medical school. From 1940 he was also professor of neuropathology in its graduate school. While there he did research on avitaminotic diseases of the nervous system. In 1913, before a convention of the German Society of Neurologists, he described in detail the eosinophilic inclusion bodies that he had discovered in the brains of patients with Parkinson's disease. By 1919 his name had become associated with these bodies.

Medical dictionary. 2011.

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  • Lewy body — Lewy bodies are abnormal aggregates of protein that develop inside nerve cells. They are identified under the microscope when histology is performed on the brain. Lewy bodies appear as spherical masses that displace other cell components. There… …   Wikipedia

  • Lewy body — /looˈi bodˈi/ noun An abnormal structure in a nerve cell, found in people with Parkinson s disease and a common type of dementia ORIGIN: FH Lewy (1885–1950), German neurologist …   Useful english dictionary

  • Lewy body — Hyaline eosinophilic concentrically laminated inclusions found in the substantia nigra and locus ceruleus of patients with Parkinsonism and Lewy body dementia …   Dictionary of molecular biology

  • Lewy-Body-Demenz — Klassifikation nach ICD 10 G31.88 Lewy Körperchen Demenz …   Deutsch Wikipedia

  • Lewy body dementia — dementia with Lewy bodies a type of dementia with similarities to both Parkinson disease and Alzheimer disease, with Lewy bodies in the cortical neurons; patients have decreased verbal fluency and visual spatial awareness …   Medical dictionary

  • Lewy body dementia — n. degenerative dementing disease of the elderly related to Lewy bodies found in the cortex of the brain characterized at first by progressive psychosis or dementia and following by characteristics of Parkinson s disease (such as involuntary… …   English contemporary dictionary

  • Lewy body — noun An abnormal aggregate of protein that develops inside nerve cells …   Wiktionary

  • Lewy — may refer to: * Levi, a biblical personage. * Lewy body, abnormal aggregates of protein that develop inside nerve cells of the brain. * Dementia with Lewy bodies, progressive brain disease associated with degenerative dementia in the elderly. *… …   Wikipedia

  • cortical Lewy body disease — a disorder characterized by a combination of parkinsonism and dementia, which typically fluctuates; abnormal proteins called Lewy bodies are found within the nerve cells of the cortex and the basal ganglia. It is the second most common cause of… …   Medical dictionary

  • cortical Lewy body disease — a disorder characterized by a combination of parkinsonism and dementia, which typically fluctuates. Visual hallucinations are common, and there is exquisite sensitivity to phenothiazine drugs. Abnormal proteins called Lewy bodies are found within …   The new mediacal dictionary

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