Lewis blood group

Lewis blood group
Lewis blood group n any of a system of blood groups controlled by a pair of dominant-recessive alleles and characterized by antigens which are released into body fluids, are adsorbed onto the surface of red blood cells, and tend to interreact with the antigens produced by secretors although they are genetically independent of them

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a blood group determined by plasma glycolipids that adhere to erythrocytic surfaces. It is based on dominant independent Le genes, but interacts with the H precursor oligosaccharides of A and B. Whereas le/le provides the “double negative” blood type Le(a−b−), Le without H gives rise to Lea, i.e., blood type Le(a+b−), and that with H gives rise to LebH, i.e., blood type Le(a−b+).

Medical dictionary. 2011.

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