glucose-6-phosphate dehydrogenase deficiency
- glucose-6-phosphate dehydrogenase deficiency
glucose-6-phosphate dehydrogenase deficiency n a hereditary metabolic disorder affecting red blood cells that is controlled by a variable gene on the X chromosome, that is characterized by a deficiency of glucose-6-phosphate dehydrogenase conferring marked susceptibility to hemolytic anemia which may be chronic, episodic, or induced by certain foods (as broad beans) or drugs (as primaquine),
and that occurs esp. in individuals of Mediterranean or African descent
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glu·cose-6-phos·phate de·hy·dro·gen·ase de·fi·cien·cy (glooґkōs fosґfāt de-hiґdro-jən-ās) the most common inborn error of metabolism, an X-linked enzyme deficiency causing varying degrees of hemolytic anemia in many millions of people around the world. It can cause favism, some drug-induced hemolytic anemias, or chronic nonspherocytic hemolytic anemia. The G6PD gene is highly polymorphic, with about 400 variants known.
Medical dictionary.
2011.
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glucose-6-phosphate dehydrogenase deficiency — glucose 6 phosphate dehydrogenase deficiency. См. дефицит глюкозо 6 фосфатдегидрогеназы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Glucose-6-phosphate dehydrogenase deficiency — ] The discovery of G6PD deficiency relieved heavily upon the testing of prisoner volunteers at Illinois State Penitentiary, although today such studies cannot be performed. When some prisoners were given the drug primaquine, some developed… … Wikipedia
glucose-6-phosphate dehydrogenase deficiency — a hereditary (X linked) condition in which the absence of the enzyme glucose 6 phosphate dehydrogenase (G6PD), which functions in carbohydrate metabolism, results in the breakdown of the red blood cells (haemolysis), usually after exposure to… … Medical dictionary
glucose-6-phosphate dehydrogenase deficiency — a hereditary (X linked) condition in which the absence of the enzyme glucose 6 phosphate dehydrogenase (G6PD), which functions in carbohydrate metabolism, results in the breakdown of the red blood cells (haemolysis), usually after exposure to… … The new mediacal dictionary
glucose-6-phosphate dehydrogenase deficiency — ▪ pathology hereditary metabolic defect characterized by an increased tendency of the red blood cells to break and release their hemoglobin (hemolysis), especially after the intake of certain drugs. The condition is caused, as the name… … Universalium
Glucose-6-phosphate dehydrogenase — NOTOC Glucose 6 phosphate dehydrogenase (G6PD) is a cytosolic enzyme in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co enzyme… … Wikipedia
glucose-6-phosphate dehydrogenase — An NADP+ enzyme catalyzing the dehydrogenation of d glucose 6 phosphate to 6 phospho d glucono δ lactone, this reaction initiating the pentose shunt. A deficiency of this enzyme can lead to severe hemolytic … Medical dictionary
Deficiency, glucose-6-phosphate dehydrogenase (G6PD) — Deficiency of G6PD is the commonest disease causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anemia due to breakup of their red blood cells… … Medical dictionary
Glucose-6-phosphate dehydrogenase (G6PD) — Deficiency of G6PD is the commonest disease causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anemia due to breakup of their red blood cells… … Medical dictionary
Дефицит Глюкозо-6Фосфат-Дегидрогеназы (Glucose- 6-Phosphate Dehydrogenase Deficiency) — наследственное заболевание, при котором у человека отсутствует фермент глюкозо 6фосфат дегидрогеназа, участвующий в углеводном обмене. Проявляется оно в детстве, вызывая увеличение печени и снижение уровня сахара в крови. В процессе лечения… … Медицинские термины
