fragility test

fragility test
fragility test n a test of the relative fragility of red blood cells made by exposing them to hypotonic solutions and determining the point at which they rupture

Medical dictionary. 2011.

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  • fragility test — noun : a test of the relative fragility of red blood cells made by exposing them to hypotonic solutions and determining the point at which they rupture …   Useful english dictionary

  • osmotic fragility test — (for spherocytosis) heparinized or defibrinated blood is placed in tubes of sodium chloride solution (pH 7.4) varying in concentration from 0.85 to 0.00 per cent (w/v); the amount of hemolysis in each tube is determined colorimetrically.… …   Medical dictionary

  • capillary fragility test — capillary resistance test tourniquet t. (def. 1) …   Medical dictionary

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Tourniquet test — For Tourniquet, see that article A tourniquet test (also known as a Rumpel Leede Capillary Fragility Test or simply a capillary fragility test) determines capillary fragility. It is a clinical diagnostic method to determine a patient s… …   Wikipedia

  • osmotic fragility — susceptibility of erythrocytes to rupture when subjected to increasingly hypotonic saline solutions; seen in some forms of hemolytic anemia and spherocytosis. See also osmotic fragility test, under test …   Medical dictionary

  • Osmotic fragility — Intervention MeSH D009996 In hematology, osmotic fragility refers to the degree of hemolysis when red blood cells are placed in a hypotonic solution. In general, osmotic fragility is inversely proportional to …   Wikipedia

  • tourniquet test — 1. (for capillary fragility) pressure is applied midway between diastole and systole for 5 minutes by a manometer cuff; the cuff is released and petechiae are counted in an area 2.5 cm in diameter, on the inner aspect of the forearm. A number… …   Medical dictionary

  • Hereditary spherocytosis — This article is about aspects of spherocytosis specific to the hereditary form of the disorder. For details that apply generally to this variant as well as others, see Spherocytosis. Hereditary spherocytosis Classification and external resources… …   Wikipedia

  • Sign — Any abnormality that indicates a disease process, such as a change in appearance, sensation, or function, that is observed by a physician when evaluating a patient. * * * 1. Any abnormality indicative of disease, discoverable on examination of… …   Medical dictionary

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