- osmotic fragility
- susceptibility of erythrocytes to rupture when subjected to increasingly hypotonic saline solutions; seen in some forms of hemolytic anemia and spherocytosis. See also osmotic fragility test, under test.
Medical dictionary. 2011.
osmotic fragility
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Osmotic fragility — Intervention MeSH D009996 In hematology, osmotic fragility refers to the degree of hemolysis when red blood cells are placed in a hypotonic solution. In general, osmotic fragility is inversely proportional to … Wikipedia
osmotic fragility test — (for spherocytosis) heparinized or defibrinated blood is placed in tubes of sodium chloride solution (pH 7.4) varying in concentration from 0.85 to 0.00 per cent (w/v); the amount of hemolysis in each tube is determined colorimetrically.… … Medical dictionary
fragility — Brittleness; liability to break, burst, or disintegrate. SYN: fragilitas. [L. fragilitas] f. of the blood SYN: osmotic f.. capillary f. the susceptibility of capillaries to breakage and extravasation of red cells under conditions of increased… … Medical dictionary
erythrocyte fragility — susceptibility of erythrocytes to hemolysis under conditions such as decreased osmotic pressure or when subjected to mechanical trauma … Medical dictionary
Hereditary spherocytosis — This article is about aspects of spherocytosis specific to the hereditary form of the disorder. For details that apply generally to this variant as well as others, see Spherocytosis. Hereditary spherocytosis Classification and external resources… … Wikipedia
fragilitas — SYN: fragility. [L.] f. crinium brittleness of the hair; a condition in which the hair of the head or face tends to split or break off. f. sanguinis SYN: osmotic fragility. * * * n. abnormal brittleness or fragility, for example of the hair… … Medical dictionary
Codocyte — This article is about the abnormally shaped red blood cell. For the endocrinology concept, see target cell. Codocytes, also known as target cells or Mexican hat cells[1],[2] are red blood cells that have the appearance of a shooting target with a … Wikipedia
Hereditary elliptocytosis — Classification and external resources Blood smear showing elliptocytes ICD 10 D … Wikipedia
Spherocytosis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 12289 ICD10 = ICD10|D|58|0|d|55 ICD9 = ICD9|282.0 ICDO = OMIM = 182900 OMIM mul = OMIM2|270970 MedlinePlus = 000530 eMedicineSubj = med eMedicineTopic = 2147 MeshID = Spherocytosis is an auto … Wikipedia
Fragilite osmotique — Fragilité osmotique Un des indices susceptibles d’être employés pour déterminer la capacité des hématies à résister à l’hémolyse à la suite d’un choc hyposmotique (hypotonique) est de mesurer la fragilité osmotique cellulaire. Ce paramètre est… … Wikipédia en Français
