amphotericin

amphotericin
am·pho·ter·i·cin .am(p)-fə-'ter-ə-sən n either of two polyenic antifungal substances obtained from a soil bacterium of the genus Streptomyces (S. nodosus) esp AMPHOTERICIN B

* * *

n.
an antifungal drug that is used to treat deep-seated fungal infections. It can be administered by mouth, but is usually given by intravenous infusion. Common side-effects include headache, fever, muscle pains, and diarrhoea. In some cases kidney damage may occur. Trade names: Abelcet, AmBisome, Amphocil, Fungilin, Fungizone.

Medical dictionary. 2011.

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  • Amphotericin B — Systematic (IUPAC) name (1R,3S,5R,6R,9 …   Wikipedia

  • amphotericin — amphotericin, amphotericin B amphotericin B . 1. an antibiotic and antifungal agent ({C47H73NO17}), produced by a strain of {Streptomyces nodosus}. It is one of a class of polyene macrolide antibiotics effective against fungal infections. It has… …   The Collaborative International Dictionary of English

  • amphotericin B — amphotericin amphotericin, amphotericin B amphotericin B . 1. an antibiotic and antifungal agent ({C47H73NO17}), produced by a strain of {Streptomyces nodosus}. It is one of a class of polyene macrolide antibiotics effective against fungal… …   The Collaborative International Dictionary of English

  • amphotericin B — n the amphotericin that is clinically useful against deep seated and systemic fungal infections * * * am·pho·ter·i·cin B (am″fə terґĭ sin) [USP] one of two polyene antifungal antibiotics (the other, amphotericin A, is not used… …   Medical dictionary

  • amphotericin B — [am΄fə ter′ə sin] n. 〚 AMPHOTERIC + IN1〛 an antibiotic compound, C46H73NO20, used in treating certain diseases caused by parasitic fungi, such as systemic candidiasis * * * …   Universalium

  • amphotericin B — [am΄fə ter′ə sin] n. [ AMPHOTERIC + IN1] an antibiotic compound, C46H73NO20, used in treating certain diseases caused by parasitic fungi, such as systemic candidiasis …   English World dictionary

  • Amphotericin B — Strukturformel Allgemeines Freiname Amphotericin B Andere Namen …   Deutsch Wikipedia

  • amphotericin B — (= Fungizone) Polyene antibiotic from Streptomyces spp. Used as a fungicide, it is cytolytic by causing the formation of pores (5 10 molecules of amphotericin in association with cholesterol) that allow passage of small molecules through the… …   Dictionary of molecular biology

  • amphotericin B — noun : the amphotericin that is useful against deep seated and systemic fungal infections …   Useful english dictionary

  • amphotericin B cholesteryl complex — amphotericin B complexed with cholesteryl sulfate in a 1:1 ratio; administered by intravenous infusion in the treatment of disseminated aspergillosis in patients refractory to or intolerant of conventional amphotericin B therapy …   Medical dictionary

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