urocanase

urocanase

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uro·can·ase (u″ro-kanґās) urocanate hydratase.

Medical dictionary. 2011.

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  • urocanase deficiency — uro·can·ase de·fi·cien·cy (u″ro kanґās) an inherited disorder of histidine catabolism caused by mutation in the UROC1 gene (locus 3q21.3), which encodes urocanate hydratase. It is characterized by excess urinary excretion of urocanic… …   Medical dictionary

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  • urocanate hydratase — uro·can·ate hy·dra·tase (u″ro kanґāt hyґdrə tās) [EC 4.2.1.49] an enzyme of the lyase class that catalyzes the reduction of urocanate to formiminoglutamate, a step in the catabolism of histidine. Deficiency of the enzyme,… …   Medical dictionary

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  • Urocanate hydratase — (also known as urocanase) is an enzyme involved in the conversion of urocanate and imidazol 4 one 5 propionic acid. Inherited deficiency of urocanate hydratase leads to elevated levels of urocanic acid in the urine, a condition known as urocanic… …   Wikipedia

  • Histidin — Strukturformel    …   Deutsch Wikipedia

  • urocanic acid — noun An intermediate in the catabolism of L histidine, transformed in the liver by urocanate hydratase (or urocanase) into 4 imidazolone 5 propionic acid and subsequently to glutamic acid …   Wiktionary

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