thyroxine

thyroxine
The l-isomer is the active iodine compound existing normally in the thyroid gland and extracted therefrom in crystalline form for therapeutic use; also prepared synthetically; used for the relief of hypothyroidism, cretinism, and myxedema.
- labeled t. SYN: radioactive t..
- radioactive t. t. in which a radioisotope of iodine (125I or 131I) is incorporated into its molecule; used in experiments tracing the metabolism of t.. SYN: labeled t., radiolabeled t., radiothyroxin.
- t. sodium a preparation obtained by the action of a limited amount of sodium carbonate upon t.; it contains between 61 and 65% of iodine. See sodium levothyroxine, sodium liothyronine.

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thy·rox·ine or thy·rox·in thī-'räk-.sēn, -sən n an iodine containing hormone C15H11I4NO4 that is an amino acid produced by the thyroid gland as a product of the cleavage of thyroglobulin, increases the metabolic rate, and is used to treat thyroid disorders called also T4

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n.
one of the hormones synthesized and secreted by the thyroid gland (see thyroid hormone). A preparation of thyroxine (levothyroxine sodium) can be administered by mouth to treat underactivity of the thyroid gland.

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thy·rox·ine (T4) (thi-rokґsin) L-3,5,3′,5′-tetraiodothyronine, the major hormone elaborated by the thyroid follicular cells, formed from thyroglobulin and transported mainly in the blood serum thyroxine-binding globulin. Its chief function is to increase the rate of cell metabolism. It is also essential for central nervous system maturation and regulates a number of other functions. Thyroxine is deiodinated in peripheral tissues (liver, kidney, and heart) to form triiodothyronine, the active “tissue” form of thyroid hormone, which is much more biologically active. A preparation of thyroxine, levothyroxine (q.v.), is used pharmaceutically. Spelled also thyroxin. thyroxinic adj

Medical dictionary. 2011.

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  • thyroxine — [ tirɔksin ] n. f. • 1933; mot angl. (1915), de thyr(oïde) et rad. de oxyde ♦ Biochim. L une des principales hormones thyroïdiennes, libérée dans le sang par l hydrolyse de la thyroglobuline, et contenant de l iode. La thyroxine augmente le… …   Encyclopédie Universelle

  • Thyroxine — Général DCI thyroxine Nom IUPAC acide 2 …   Wikipédia en Français

  • thyroxine — (n.) from thyro , comb. form of THYROID (Cf. thyroid), + OXY (Cf. oxy ) + indole + chemical suffix INE (Cf. ine) (2). So called from the original description of its composition …   Etymology dictionary

  • thyroxine — [thī räks′inthī räk′sēn΄, thī räk′sin] n. [ THYR(O) + OX(Y) + INE3] a colorless, crystalline compound, C15H11I4NO4, the active hormone of the thyroid gland, often prepared synthetically and used in treating goiter, cretinism, and myxedema: also… …   English World dictionary

  • thyroxine — /thuy rok seen, sin/, n. 1. Biochem. the thyroid gland hormone that regulates the metabolic rate of the body. 2. Pharm. a commercial form of this compound, obtained from the thyroid glands of animals or synthesized, used in the treatment of… …   Universalium

  • thyroxine — Thyroid Thy roid, a. [Gr. qyreoeidh s shield shaped; qyreo s a large, oblong shield (from qy ra a door) + e i^dos form: cf. F. thyro[ i]de, thyr[ e]o[ i]de.] 1. Shaped like an oblong shield; shield shaped; as, the thyroid cartilage. [1913… …   The Collaborative International Dictionary of English

  • thyroxine — A hormone that is made by the thyroid gland and contains iodine. Thyroxine increases the rate of chemical reactions in cells and helps control growth and development. Thyroxine can also be made in the laboratory and is used to treat thyroid… …   English dictionary of cancer terms

  • thyroxine — tetraiodothyronine; = T4; n. the principal hormone synthesized and secreted into the bloodstream by the thyroid gland (see thyroid hormone). Most of it is converted to a more metabolically active form, triiodothyronine, within the peripheral… …   The new mediacal dictionary

  • thyroxine — tiroksinas statusas T sritis chemija apibrėžtis Skydliaukės hormonas. formulė HO(I₂)C₆H₂OC₆H₂(I₂)CH₂CH(NH₂)COOH atitikmenys: angl. thyroxine; 3,5,3ˊ,5ˊ tetraiodothyronine rus. тироксин; 3,5,3ˊ,5ˊ тетраиодтиронин ryšiai: sinonimas – 3,5,3ˊ,5ˊ… …   Chemijos terminų aiškinamasis žodynas

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