A substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood; in the presence of calcium ions t. is necessary for the conversion of prothrombin to thrombin, an important step in coagulation of blood. It is now generally believed that t. activity may be developed through blood (intrinsic) or tissue (extrinsic) systems. Tissue t. (factor III) interacts with factor VII and calcium to activate factor X; active factor X combines with factor V in the presence of calcium and phospholipid to produce t. activity (also commonly called t.). SYN: platelet tissue factor, thrombokinase, thrombozyme, tissue factor, zymoplastic substance.

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throm·bo·plas·tin .thräm-bō-'plas-tən n a complex enzyme that is found in brain, lung, and other tissues and esp. in blood platelets and that functions in the conversion of prothrombin to thrombin in the clotting of blood called also thrombokinase

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a substance formed during the earlier stages of blood coagulation. It acts as an enzyme, converting the inactive substance prothrombin to the enzyme thrombin.

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throm·bo·plas·tin (throm″bo-plasґtin) factor III; see under coagulation factors, at factor.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Thromboplastin — Vorhandene Strukturdaten: siehe UniProt Ei …   Deutsch Wikipedia

  • Thromboplastin — ⇒ Thrombokinase …   Deutsch wörterbuch der biologie

  • thromboplastin — [thräm΄bōplas′tin] n. [ THROMBO + PLAST + IN1] a substance released from blood platelets and injured body tissues that assists in the clotting of the blood by initiating the conversion of prothrombin to thrombin …   English World dictionary

  • thromboplastin — noun Etymology: International Scientific Vocabulary, from thromboplastic Date: 1911 a complex enzyme found especially in platelets that functions in the conversion of prothrombin into thrombin in the clotting of blood …   New Collegiate Dictionary

  • thromboplastin — Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin) …   Dictionary of molecular biology

  • thromboplastin — /throm beuh plas tin/, n. 1. Biochem. a lipoprotein in the blood that converts prothrombin to thrombin. 2. Pharm. a commercial form of this substance, obtained from the brains of cattle, used chiefly as a local hemostatic and as a laboratory… …   Universalium

  • thromboplastin — noun A protease that converts prothrombin to thrombin during the clotting of blood …   Wiktionary

  • Thromboplastin — Throm|bo|plas|tin [↑ plast u. ↑ in (3)], das; s, e; Syn.: Thrombokinase, Faktor III bzw. Xa: Lipoproteine, die als Faktoren der Blutgerinnung (↑ Fibrin) Prothrombin in ↑ Thrombin überführen. * * * Thrombo|plast …   Universal-Lexikon

  • Thromboplastin — Thrombo|plasti̱n [zu ↑Thrombus und gr. πλασσεινThromboplastin= bilden, gestalten] s; s, e: andere Bez. für ↑Thrombokinase …   Das Wörterbuch medizinischer Fachausdrücke

  • thromboplastin — n. substance found in blood platelets and used to stop bleeding …   English contemporary dictionary

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