- A sulfonamide (acid-azosulfa compound) with a marked affinity for connective tissues, especially for those rich in elastin, used in chronic ulcerative colitis; it is broken down in the body to aminosalicylic acid and sulfapyridine. SYN: salicylazosulfapyridine.
* * *sul·fa·sal·a·zine or chiefly Brit sul·pha·sal·a·zine .səl-fə-'sal-ə-.zēn n a sulfonamide C18H14N4O5S used in the treatment of chronic ulcerative colitis called also salicylazosulfapyridine
* * *n.a drug of the sulphonamide group, used in the treatment of ulcerative colitis and Crohn's disease and (for its anti-inflammatory action) rheumatoid arthritis. It is given by mouth or in the form of suppositories. The most common side-effects are nausea, loss of appetite, and raised temperature. Trade name: Salazopyrin.
* * *sul·fa·sal·a·zine (sul″fə-salґə-zēn) [USP] an antibacterial sulfonamide used orally or rectally in the prophylaxis and treatment of inflammatory bowel disease, and orally as a disease-modifying antirheumatic drug in the treatment of rheumatoid arthritis.
Medical dictionary. 2011.