succinate semialdehyde

succinate semialdehyde
An intermediate in the catabolism of γ-aminobutyrate.
- s. dehydrogenase an enzyme that catalyzes the reaction of s. and either NAD+ or NADP+ to form succinate and NADH (or NADPH); a deficiency of this enzyme is associated with 4-hydroxybutyric aciduria.

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γ-hydroxybutyric acid.

Medical dictionary. 2011.

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  • Succinate-semialdehyde dehydrogenase — In enzymology, a succinate semialdehyde dehydrogenase (EC number|1.2.1.24) is an enzyme that catalyzes the chemical reaction:succinate semialdehyde + NAD+ + H2O ightleftharpoons succinate + NADH + 2 H+The 3 substrates of this enzyme are succinate …   Wikipedia

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  • succinate-semialdehyde dehydrogenase — suc·ci·nate semi·al·de·hyde de·hy·dro·gen·ase (sukґsĭ nāt sem″e alґdə hīd de hiґdro jən ās) [EC 1.2.1.24] an enzyme of the oxidoreductase class that catalyzes the oxidation of γ hydroxybutyric acid to… …   Medical dictionary

  • semialdehyde — The monoaldehyde of a dicarboxylic acid, so called because half the COOH groups of the original acid are reduced to the aldehyde while the other half are unchanged; e.g., glutamic acid γ s., OHC–CH2CH2CH(NH3)+–COO−. Many semialdehydes are… …   Medical dictionary

  • Succinic semialdehyde dehydrogenase deficiency — Infobox Disease Name = PAGENAME Caption = Gamma Hydroxybutyric acid DiseasesDB = 29825 ICD10 = ICD9 = ICDO = OMIM = 271980 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Succinic semialdehyde dehydrogenase deficiency (SSADHD), also known …   Wikipedia

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  • ALDH5A1 (gene) — Aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase), also known as ALDH5A1, is a human gene.cite web | title = Entrez Gene: ALDH5A1 aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase)|… …   Wikipedia

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • 2-oxoglutarate decarboxylase — In enzymology, a 2 oxoglutarate decarboxylase (EC number|4.1.1.71) is an enzyme that catalyzes the chemical reaction:2 oxoglutarate ightleftharpoons succinate semialdehyde + CO2Hence, this enzyme has one substrate, 2 oxoglutarate, and two… …   Wikipedia

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