pyrroline-5-carboxylate reductase

pyrroline-5-carboxylate reductase
An oxidoreductase reversibly reducing 1-pyrroline-5-carboxylate to l-proline with NAD(P)H; a deficiency of this enzyme is associated with type I hyperprolinemia. SYN: proline dehydrogenase, proline oxidase.

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pyr·ro·line-5-car·box·y·late re·duc·tase (pirґo-lēn kahr-bokґsə-lāt re-dukґtās) [EC 1.5.1.2] an enzyme of the oxidoreductase class that catalyzes the irreversible reduction of Δ1-pyrroline 5-carboxylate to proline, using NADPH (or NADH) as an electron donor; the reaction is the final step in the biosynthesis of proline from glutamate or ornithine. The enzyme may also reduce the 3-hydroxy analog of pyrroline 5-carboxylate to form hydroxyproline.

Medical dictionary. 2011.

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  • Pyrroline-5-carboxylate reductase — In enzymology, a pyrroline 5 carboxylate reductase (EC number|1.5.1.2) is an enzyme that catalyzes the chemical reaction:L proline + NAD(P)+ ightleftharpoons 1 pyrroline 5 carboxylate + NAD(P)H + H+The 3 substrates of this enzyme are L proline,… …   Wikipedia

  • Pyrroline-2-carboxylate reductase — In enzymology, a pyrroline 2 carboxylate reductase (EC number|1.5.1.1) is an enzyme that catalyzes the chemical reaction:L proline + NAD(P)+ ightleftharpoons 1 pyrroline 2 carboxylate + NAD(P)H + H+The 3 substrates of this enzyme are L proline,… …   Wikipedia

  • pyrroline-2-carboxylate reductase — An oxidoreductase reducing 1 pyrroline 2 carboxylate to l proline with NAD(P)H. SYN: proline dehydrogenase, proline oxidase …   Medical dictionary

  • 1-Pyrroline-5-carboxylic acid — IUPAC name 3,4 dihydro 2H pyrrole 2 carboxylic acid …   Wikipedia

  • Acide 1-pyrroline-5-carboxylique — Structure de l acide 1 pyrroline 5 carboxylique Général No CAS …   Wikipédia en Français

  • PYCR — pyrroline 5 carboxylate reductase …   Medical dictionary

  • PYCR — • pyrroline 5 carboxylate reductase …   Dictionary of medical acronyms & abbreviations

  • PYCR1 — Pyrroline 5 carboxylate reductase 1, also known as PYCR1, is a human gene.cite web | title = Entrez Gene: PYCR1 pyrroline 5 carboxylate reductase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5831|… …   Wikipedia

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • proline — Pyrrolidine 2 carboxylic acid; the l isomer is found in proteins, especially the collagens. SYN: pyrrolidine 2 carboxylate. p. aminopeptidase SYN: p. iminopeptidase. p. dehydrogenase SYN: pyrroline 2 carboxylate reductase, pyrroline 5 carboxylate …   Medical dictionary

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