Pyrrolidine-2-carboxylic acid; the l-isomer is found in proteins, especially the collagens. SYN: pyrrolidine-2-carboxylate.
- p. aminopeptidase SYN: p. iminopeptidase.
- p. dehydrogenase SYN: pyrroline-2-carboxylate reductase, pyrroline-5-carboxylate reductase.
- p. dipeptidase an enzyme cleaving aminoacyl-l-p. bonds in dipeptides containing a C-terminal p. residue; a deficiency of this enzyme results in hyperimidodipeptiduria. SYN: imidodipeptidase, peptidase D, prolidase.
- p. iminopeptidase a hydrolase cleaving l-prolyl residues from the N-terminal position in peptides. SYN: p. aminopeptidase.
- p. oxidase SYN: pyrroline-2-carboxylate reductase, pyrroline-5-carboxylate reductase.
- p. racemase an enzyme that reversibly converts d-p. to l-p..
- d-p. reductase an oxidoreductase reversibly reacting d-p. with NADH to produce 5-aminovalerate and NAD+.

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pro·line 'prō-.lēn n an amino acid C5H9NO2 that can be synthesized by animals from glutamate abbr. Pro

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an amino acid found in many proteins.

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pro·line (Pro) (P) (proґlēn) a nonessential amino acid, 2-pyrrolidinecarboxylic acid, a major constituent of collagen (see tropocollagen). See also table at amino acid. [USP] a preparation of proline used as a dietary supplement.

Medical dictionary. 2011.

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