1-pyrroline-5-carboxylate dehydrogenase
- 1-pyrroline-5-carboxylate dehydrogenase
-
* * *
1-pyr·ro·line-5-car·box·y·late de·hy·dro·gen·ase (pirґo-lēn kahr-bokґsə-lāt de-hiґdro-jən-ās) [EC 1.5.1.12] an enzyme of the oxidoreductase class that catalyzes the dehydrogenation of Δ1-pyrroline 5-carboxylate to glutamate, using NAD+ as an electron acceptor; the reaction is a step in the degradation of proline and excess ornithine. The enzyme can also oxidize the 3-hydroxy derivative of Δ1-pyrroline 5-carboxylate to form 4-hydroxyglutamate. Deficiency of the enzyme, an autosomal recessive trait, is the cause of hyperprolinemia, type II.
Medical dictionary.
2011.
Look at other dictionaries:
1-Pyrroline-5-carboxylate dehydrogenase — In enzymology, a 1 pyrroline 5 carboxylate dehydrogenase (EC number|1.5.1.12) is an enzyme that catalyzes the chemical reaction: (S) 1 pyrroline 5 carboxylate + NAD+ + 2 H2O ightleftharpoons L glutamate + NADH + H+The three substrates of this… … Wikipedia
pyrroline-5-carboxylate reductase — An oxidoreductase reversibly reducing 1 pyrroline 5 carboxylate to l proline with NAD(P)H; a deficiency of this enzyme is associated with type I hyperprolinemia. SYN: proline dehydrogenase, proline oxidase. * * * pyr·ro·line 5 car·box·y·late… … Medical dictionary
pyrroline-2-carboxylate reductase — An oxidoreductase reducing 1 pyrroline 2 carboxylate to l proline with NAD(P)H. SYN: proline dehydrogenase, proline oxidase … Medical dictionary
1-Pyrroline-5-carboxylic acid — IUPAC name 3,4 dihydro 2H pyrrole 2 carboxylic acid … Wikipedia
Proline dehydrogenase — In enzymology, a proline dehydrogenase (EC number|1.5.99.8) is an enzyme that catalyzes the chemical reaction:L proline + acceptor ightleftharpoons (S) 1 pyrroline 5 carboxylate + reduced acceptorThus, the two substrates of this enzyme are L… … Wikipedia
proline dehydrogenase — pro·line de·hy·dro·gen·ase (proґlēn de hiґdro jən ās) [EC 1.5.99.8] an enzyme of the oxidoreductase class that catalyzes the dehydrogenation of proline to form Δ1 pyrroline 5 carboxylate, using ubiquinone as an electron… … Medical dictionary
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
Hyperprolinemia — Infobox Disease Name = PAGENAME Caption = Proline Width = 150px DiseasesDB = 29674 ICD10 = ICD10|E|72|5|e|72 ICD9 = ICD9|270.8 ICDO = OMIM = 239500 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Hypeprolinemia, also referred to as… … Wikipedia
ALDH4A1 — Aldehyde dehydrogenase 4 family, member A1, also known as ALDH4A1, is a human gene.cite web | title = Entrez Gene: ALDH4A1 aldehyde dehydrogenase 4 family, member A1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… … Wikipedia
Amino acid — This article is about the class of chemicals. For the structures and properties of the standard proteinogenic amino acids, see Proteinogenic amino acid. The generic structure of an alpha amino acid in its unionized form … Wikipedia
