Hexosaminidase A

Hexosaminidase A
Deficiency of this enzyme causes Tay-Sachs disease, a progressive, fatal neurologic disorder concentrated in people of European Jewish (Ashkenazi) descent.

* * *

hexosaminidase A n the more thermolabile hexosaminidase that is deficient in both Tay-Sachs disease and Sandhoff's disease called also hex A

* * *

β-N-acetylhexosaminidase, isozyme A.

Medical dictionary. 2011.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • hexosaminidase B — n the more thermostable hexosaminidase that is deficient in Sandhoff s disease but present in elevated quantities in Tay Sachs disease called also hex B * * * β N acetylhexosaminidase, isozyme B …   Medical dictionary

  • hexosaminidase — hexosaminidase. См. гексозаминидаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Hexosaminidase — β N acetylhexosaminidase Hexosaminidase A (Hex A) Identifiers EC number 3.2.1.52 …   Wikipedia

  • hexosaminidase — General term for enzymes cleaving N acetylhexose ( e.g., N acetylglucosamine) residues from gangliosidelike oligosaccharides. At least four specific enzymes carrying out this type of reaction are known: α N acetyl d galactosaminidase, α N acetyl… …   Medical dictionary

  • hexosaminidase — noun Etymology: hexose + amino + ide + ase Date: 1969 either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases (as Tay Sachs disease) …   New Collegiate Dictionary

  • hexosaminidase — Enzyme involved in the metabolism of gangliosides. Deficient in Tay Sachs disease …   Dictionary of molecular biology

  • hexosaminidase — noun Any enzyme that catalyzes the hydrolysis of terminal hexosamine residues in hexosaminides …   Wiktionary

  • hexosaminidase — hex·os·a·min·i·dase …   English syllables

  • hexosaminidase — ˌhekˌsäsəˈminə̇ˌdās, āz noun ( s) Etymology: hexosamine + ide (I) + ase : either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases (as Tay Sachs disease) …   Useful english dictionary

  • Hexosaminidase A deficiency — Lack of an enzyme that causes Tay Sachs disease. Hex A deficiency results in failure to process a lipid (a fat) which accumulates and is deposited in the brain and other tissues, to their detriment. The lipid that is deposited is called GM2… …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”