- o. phosphoribosyltransferase a phosphoribosyltransferase synthesizing orotidylate and pyrophosphate from o. and 5-phospho-α-d-ribosyl-1-pyrophosphate; this enzyme is a part of pyrimidine biosynthesis; a deficiency of this enzyme is associated with orotic aciduria type I. Cf.:uridylic acid synthase. SYN: OMP pyrophosphorylase, orotidylic acid phosphorylase, orotidylic acid pyrophosphorylase.

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oro·tate 'ȯr-ə-.tāt n a salt of orotic acid also the anion of such a salt

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or·o·tate (orґo-tāt) a dissociated form of orotic acid.

Medical dictionary. 2011.

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