orotate phosphoribosyltransferase
- orotate phosphoribosyltransferase
- (OPRT) or·o·tate phos·pho·ri·bo·syl·trans·fer·ase (OPRT) (orґo-tāt fos″fo-ri″bo-səl-transґfər-ās) [EC 2.4.2.10] an enzyme activity of the transferase class that catalyzes the transfer to orotate of a ribosyl group from phosphoribosylpyrophosphate (PRPP) to form orotidine 5′-phosphate as a step in the synthesis of pyrimidine nucleotides. The catalytic sites for this activity and for orotidine 5′-phosphate decarboxylase (ODC) activity occur on a single protein, called UMP synthase; deficiency of both activities, an autosomal recessive trait, results in hereditary oroticaciduria, type I.
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2011.
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Orotate phosphoribosyltransferase — S. cerevisiae orotate phosphoribosyl transferase bound to its substrates. From PDB file 2PSI.[ … Wikipedia
orotate — A salt or ester of orotic acid. o. phosphoribosyltransferase a phosphoribosyltransferase synthesizing orotidylate and pyrophosphate from o. and 5 phospho α d ribosyl 1 pyrophosphate; this enzyme is a part of pyrimidine … Medical dictionary
OPRTase — orotate phosphoribosyltransferase … Medical dictionary
OPRT — • orotate phosphoribosyltransferase … Dictionary of medical acronyms & abbreviations
OPRTase — • orotate phosphoribosyltransferase … Dictionary of medical acronyms & abbreviations
OPRT — orotate phosphoribosyltransferase * * * orotate phosphoribosyltransferase … Medical dictionary
Uridine monophosphate synthetase — PDB rendering based on 2eaw … Wikipedia
Orotidine 5'-phosphate decarboxylase — E. coli OMP decarboxylase.[1] Identifiers EC number … Wikipedia
Phosphoribosylpyrophosphate — Structure du phosphoribosylpyrophosphate Général Synonymes α D … Wikipédia en Français
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
