monobactam

monobactam
A class of antibiotic that has a monocyclic β-lactam nucleus and is structurally different from other β-lactams; e.g., aztreonam.

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mono·bac·tam .män-ō-'bak-tam n any of the class of beta-lactam antibiotics (as aztreonam) with a monocyclic ring structure

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mon·o·bac·tam (mon″o-bakґtam) a class of synthetic antibiotics having a monocyclic β-lactam nucleus.

Medical dictionary. 2011.

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  • Monobactam — Aztreonam. (The square is the β lactam. There is a second thiazole ring, but it is not fused to the β lactam ring.) …   Wikipedia

  • Monobactam — Monobactame (beispielsweise Aztreonam) sind Antibiotika, die von gramnegativen Bakterien produziert und synthetisch modifiziert werden. Sie enthalten nur noch einen monozyklischen β Lactam Ring. Sie sind β Lactamase stabil, werden jedoch aus dem… …   Deutsch Wikipedia

  • monobactam — noun Any of various beta lactam compounds wherein the beta lactam ring is alone, not fused to another ring …   Wiktionary

  • Monobactam — Mo|no|bac|tam [vermutlich Kurzw. aus monocyclisch u. Beta Lactam], das; s, e: Gruppenbez. für aus Bakterien isolierte oder synthetisierte Azetidinonsulfonsäure Derivate, die antibiotisch wirksam sind …   Universal-Lexikon

  • Aztreonam — Systematic (IUPAC) name 2 ({[(1Z …   Wikipedia

  • Tigemonam — IUPAC name 2 [[1 (2 Amino 1,3 thiazol 4 yl) 2 [[(3S) 2,2 dimethyl 4 oxo 1 sulfooxyazetidin 3 yl]amino] 2 oxoethylidene]amino]oxyacetic …   Wikipedia

  • Beta-lactamase — Beta lactamases are enzymes (EC number|3.5.2.6) produced by some bacteria and are responsible for their resistance to beta lactam antibiotics like penicillins, cephalosporins, cephamycins, ertapenems and carbapenems. These antibiotics have a… …   Wikipedia

  • Beta-lactam antibiotic — β lactam antibiotics are a broad class of antibiotics that include penicillin derivatives, cephalosporins, monobactams, carbapenems, and β lactamase inhibitors, that is, any antibiotic agent that contains a β lactam nucleus in its molecular… …   Wikipedia

  • aztreonam — A synthetic bactericidal monolactam antibiotic with a wide spectrum of activity against Gram negative aerobic pathogens. * * * az·tre·o·nam .az trē ō .nam, az trē n a synthetic monobactam antibiotic C13H17N5O8S2 used esp. against gram negative… …   Medical dictionary

  • Bactericide — A bactericide or bacteriocide is a substance that kills bacteria and, preferably, nothing else. Bactericides are either disinfectants, antiseptics or antibiotics. Important Functional Groups in a Bactericidal Substance The most used bactericidal… …   Wikipedia

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