lymphohistiocytosis

lymphohistiocytosis
Proliferation or infiltration of lymphocytes and histiocytes.
- familial erythrophagocytic l. (FEL) SYN: familial hemophagocytic l..
- familial hemophagocytic l. (FMLH) an extremely rare, usually fatal disease of childhood characterized by multiorgan infiltration with activated macrophages and lymphocytes. The disease is often familial and appears to be inherited as an autosomal recessive trait. SYN: familial erythrophagocytic l..

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lym·pho·his·tio·cy·to·sis (lim″fo-his″te-o-si-toґsis) lymphocytosis with histiocytosis.

Medical dictionary. 2011.

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  • lymphohistiocytosis — noun The abnormal presence of histiocytes in the blood …   Wiktionary

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  • familial hemophagocytic lymphohistiocytosis — an autosomal recessive, genetically heterogeneous type of hemophagocytic lymphohistiocytosis; it is characterized by anemia, granulocytopenia, thrombocytopenia, intense phagocytosis of red blood cells, diffuse proliferation of histiocytes of… …   Medical dictionary

  • Hemophagocytic lymphohistiocytosis — A rare, cancer like disorder in which both histiocytes and lymphocytes start to proliferate and attack body tissues or organs. It can be an inherited condition, or it can occur as a result of immunosuppression (as in organ transplants) or… …   Medical dictionary

  • erythrophagocytic lymphohistiocytosis — hemophagocytic l …   Medical dictionary

  • hemophagocytic lymphohistiocytosis — HLH. A rare disorder in which histiocytes and lymphocytes (types of white blood cells) build up in organs including the skin, spleen, and liver, and destroy other blood cells. HLH may be inherited or caused by certain conditions or diseases,… …   English dictionary of cancer terms

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  • Perforin — 1 (pore forming protein), also known as PRF1, is a human gene.cite web | title = Entrez Gene: PRF1 perforin 1 (pore forming protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5551| accessdate = ]… …   Wikipedia

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  • Histiocytosis — Classification and external resources ICD 10 C96.1, D76.0 ICD 9 …   Wikipedia

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